RNA helicases are ubiquitous enzymes whose modification of RNA secondary structure is known to regulate RNA function. The pathways controlling RNA helicase expression, however, have not been well characterized. Expression of the cyanobacterial RNA helicase, crhR, is regulated in response to environmental signals that alter the redox poise of the electron transport chain, including light and tem...

BACKGROUND Biological phenotypes are described as "canalized" if they are robust to minor variation of environment and/or genetic background. The existence of a robust phenotype logically implies that some underlying mechanism must be variable, in the sense of "able to vary", in order to compensate for variation in the environment and/or genetic effects. Several lines of evidence lead to the co...

Barley powdery mildew resistance (PM-R) genes control different infection phenotypes against avirulent strains of Blumeria graminis f. sp. hordei (Bgh). A subset of seven Pallas isolines, containing the PM-R genes Mla1, Mla12, Mlg, Mlk, Mlp and mlo5, revealed fast-, intermediateand slow-acting infection phenotypes. Scanning electron microscopy revealed the extent of Bgh development on each geno...

Persistent infection of the chestnut blight fungus Cryphonectria parasitica with the prototypic hypovirus CHVI-713 results in attenuation of fungal virulence (hypo-virulence) and reduced accumulation of the GTP-binding (G) protein a subunit CPG-1. Transgenic cosuppression of CPG-1 accumulation in the absence of virus infection also confers hypovirulence. We now report the use of mRNA differenti...

We demonstrate that two independent mechanisms act on maternally derived cyclin B transcripts to concentrate the transcripts at the posterior pole of the Drosophila oocyte and at the cortex of the syncytial embryo. The cortical accumulation occurs because the cyclin B transcript is concentrated around nuclei and comigrates with them to the cortex. The perinuclear localisation of the transcript ...