purpose: to present a case of herpes zoster ophthalmicus (hzo) with consequent posterior ischemic optic neuropathy (pion). case report: a 58-year-old woman with a history of hzo in her right eye which was under treatment presented with loss of vision to no light perception. on examination, positive relative afferent pupillary defect was detected; however the optic disc was normal on ophthalmosc...

Introduction Ethambutol is a promising antituberculous drug which has been proposed as a replacement for PAS in the first-line triple therapy of tuberculosis. This suggestion is based on its equal or possible superior effectiveness in man, compared with PAS (Donomae & Yamamoto, 1966; Bobrowitz, 1966), whilst having few toxic effects in the doses at present recommended (Tubercle, 1966; Tiburtius...

BACKGROUND AND PURPOSE Brain white matter is frequently affected in mitochondrial diseases; optic atrophy gene 1-autosomal dominant optic atrophy and Leber hereditary optic neuropathy are the most frequent mitochondrial monosymptomatic optic neuropathies. In this observational study, brain white matter microstructure was characterized by DTI in patients with optic atrophy gene 1-autosomal domin...

INTRODUCTION Chronic relapsing inflammatory optic neuropathy is a recently described form of recurrent isolated subacute optic neuropathy. The condition is highly responsive to systemic steroid treatment and prone to relapse on steroid withdrawal. A complete work up for demyelination, autoimmune disease and sarcoidosis must be made before considering chronic relapsing inflammatory optic neuropa...

BACKGROUND AND PURPOSE The relation between anterior ischemic optic neuropathy and carotid artery atherosclerotic disease is unclear. We studied patients with anterior ischemic optic neuropathy to determine if they had an increased occurrence of carotid artery stenosis. METHODS Fifteen consecutive patients with anterior ischemic optic neuropathy were evaluated prospectively for cervical carot...

purpose: to compare ophthalmic artery velocity in eyes with nonarteritic anterior ischemic optic neuropathy (naion) with that of normal fellow eyes. methods: in this case-control study, 20 patients with unilateral naion and disease onset less than 8 weeks, were enrolled. using color doppler imaging, mean, maximum systolic and end diastolic ophthalmic artery velocities were evaluated. the result...

although uncommon, traumatic optic neuropathy (ton) is an important cause of visual loss. different therapeutic approaches including different dosages of steroids, surgical decompression of optic canal and observation alone have been suggested but there has been no conclusive evidence to establish a standard approach to this devastating cause of visual loss. to determine the effectiveness of in...