Upsalite® is a mesoporous magnesium carbonate synthesized without using surfactants and therefore highly attractive from environmental and production economy points of view. The material has recently been suggested as drug delivery vehicle and as topical bacteriostatic agent. In order to continue exploring these and other bio-related applications of the material, primary biocompatibility studie...

background: suicide is a problem worldwide and occupation is an important risk factor. in the last decade, 55 200 deaths in the us were attributed to occupational risk factors. objective: to determine if toxic metal exposure was associated with suicide risk among paducah gaseous diffusion plant (pgdp) workers. methods: we assembled a cohort of 6820 nuclear industry workers employed from 1952 to...

The chromium (51Cr) release assay has been widely used for viability measurements, even though it has major disadvantages such as high manual workload and poor time resolution. By the use of LigandTracer 51Cr release viability measurements on adherent cells can be significantly simplified and improved. LigandTracer enables a time-resolved detection of 5SCr in target cells, with the result that ...

Microbe-metal interactions in aquatic environments and their exact role in transport and transformations of toxic metals are poorly understood. This paper will briefly review our understanding of these interactions. Ongoing research in Lake Chapala, Mexico, the major water source for the City of Guadalajara, provides an opportunity to study the microbiological aspects of metal-cycling in the wa...

As a number of reviews on different aspects of the toxicology of the PCBs have been written recently (1-4) no effort has been made in this report to give a complete outline of the animal toxicology. The material summarized in this report consists predominantly of more recently published information on toxic effects of PCBs in mammals and experimental studies in birds. Since Nelson et al. (3) di...

Colicine V has been obtained from the culture medium in which the colicinogenic bacillus E. coli K357 L_T is grown. The material is electrophoretically homogeneous and proves to be a lipocarbohydrate protein complex identical with the type-specific O antigen of the parent bacillus. Colicine V is toxic both for mice and for rabbits and readily stimulates the elaboration of precipitins and bacter...

The toxicity of endodontic materials is reviewed. The patient may be exposed by constituents leaching from the unset and set sealer and by accidental overfilling of the root canal. For most patients the exposure is believed to be below the threshold for a toxic effect. Most sealers exhibited a cytotoxic response, especially unset and the responses diminished with time after setting. Unset and n...

Amyloidosis is characterized by accumulation of amorphous, proteinaceous material in various organs and tissues of the body. Amyloid may accumulate in the thyroid gland in cases of medullary thyroid carcinoma and systemic amyloidosis. Amyloid accumulates extracellularly in the thyroid parenchyma and disrupts the normal follicular patterns. Most of the cases reported up to now were clinically eu...