this study aimed to observe the protective effects of sufentanil pretreatment on rat cerebral injury during cardiopulmonary bypass (cpb) and to explore the underlying mechanism. twenty-four male adult sprague dawley (sd) rats were divided into 4 groups. then, the rat cpb model was established. a 14g trocar was inserted into the atrium dextrum. for rats in s1 and s5 groups, sufentanil (1 µg•kg-1...

BACKGROUND Calcium is known to be major mediator in ischemic neuronal cell death. Recent studies have shown that elevated serum calcium levels at admission in patients with stroke have been associated with less severe clinical deficits and with better outcomes. AIM The aim of this to determine the correlation between serum calcium (total, corrected, and ionized) and infarct size (IS) in patie...

In the absence of definite experimental evidence, it has generally been assumed that the symptoms of tetany associated with increases in serum pH are due to a decrease in the concentration of ionic calcium. However, by means of the frog heart method, McLean and Hastings (1) were unable to demonstrate any significant change in calcium ions with change in pH. Because of the relatively narrow pH r...

OBJECTIVE Biological markers that could aid in the detection of ovarian cancer are urgently needed. Many ovarian cancers express parathyroid hormone-related protein, which acts to raise calcium levels in serum. Thus, we hypothesized that high serum calcium levels might predict ovarian cancer. METHODS We examined the associations between total and ionized serum calcium and ovarian cancer morta...

Total and ionized calcium and other related parameters were measured in 34 patients with multiple myeloma. Hypercalcemia was not a major feature of the group of patients studied with only three patients exhibiting marked increases in total (Ca total) and ionized (Ca++) calcium concentrations. The Ca++/Ca total ratio was also maintained within relatively narrow limits. No major differences were ...

The research included Estimation of some biochemical parameters like Hepcidin hormone , parathyroid hormone, vitamin D3 ,iron ,calcium, total cholesterol, triglycerides, HDL, VLDL, paraoxonase, glutathione-s-transferase, BMI ,and ceruloplasmin in serum women with osteoporosis after menopausal, the results shewed a decrease levels (Hepcidin D, calcium, hemoglobin, BMI, and albumin) blood patient...

The amount of calcium bound to protein was measured in 30 patients with differing diseases and varying degrees of hypoalbuminaemia. Total serum calcium increased directly with both serum albumin and ultrafilterable calcium concentrations. The estimated amount of calcium bound per gram of albumin varied inversely with the albumin concentration, decreasing from 2.1 to 1.0 mg calcium/g albumin as ...

Objective. Altered calcium homeostasis has been linked to increased intima-media thickness (IMT) and plaques. We aimed to investigate whether serum 25-hydroxyvitamin D (25(OH)D) and serum calcium are associated with IMT and plaques in nonsmoking population. Methods. Ultrasound of the right carotid artery with the measurements of IMT and plaques was performed in 4194 nonsmoking subjects with ava...

Hypercalcaemia is often thought to provide important clues to the presence of unsuspected illness. A presumptive diagnosis of hypercalcaemia may often be made on an elevated total serum calcium concentration although it should, strictly speaking, refer to an elevation in the physiologically important ionized (free) calcium concentration. Pseudohypercalcaemia is rare, but should be excluded befo...