PURPOSE We studied morphologic changes of the retinal vasculature in eyes with central retinal vein occlusion (CRVO) through the use of optical coherence tomography (OCT). METHODS Major retinal vessels in 35 eyes from 35 consecutive patients with acute CRVO were examined prospectively and longitudinally with sequential thin sectioning and circumpapillary scanning. Anteroposterior venous tortu...

Tortuous microvessels alter blood flow and stimulate thrombosis but the physical mechanisms are poorly understood. Both tortuous microvessels and abnormally large platelets are seen in diabetic patients. Thus, the objective of this study was to determine the physical effects of arteriole tortuosity and platelet size on the microscale processes of thrombotic occlusion in microvessels. A new latt...

Diffusion in pure gels and gels with immobilized cells was analyzed. A model of diffusion assuming a homogeneous cell distribution in gel was improved by introducing a tortuosity value. By theoretical analysis and numerical modeling it was shown that the tortuosity of a gel with immobilized cells is the product of two factors: (1) tortuosity generated by the cells, Tc, and (2) tortuosity of the...

In the present study, the effect of porosity on the cathode microstructure (50:50 wt. % LSM: YSZ) of a Solid Oxide Fuel Cell (SOFC) has been examined. A 3-D finite element method for Mixed Ionic and Electronic Conducting Cathodes (MIEC) is presented to study the effects of porosity on cell performance. Each microstructure was realized using the Monte Carlo approach with the isotropic type of gr...

An efficient procedure is presented for the evaluation of solid oxide fuel cell (SOFC) anode microstructure triple phase boundary length (TPBL). Triple phase boundary- the one that is common between three phases of the microstructure- has a great influence on the overall efficiency of SOFC because all electrochemical reactions of anode take place in its vicinity. Therefore, evaluation of TP...

Plus disease is a major indicator for treatment in retinopathy of prematurity (ROP), and computer-assisted image analysis of vessel caliber and tortuosity in the posterior pole may indicate disease progression and severity. We sought to determine whether semiautomated digital analysis of posterior pole vessels using narrow field images with varying severity of ROP correlated with vessel width a...

PURPOSE Retinopathy of prematurity (ROP) is a potentially blinding vasoproliferative disease. There is no standardized way to quantify plus disease (tortuous and dilated retinal vessels) or characterize abnormal recovery during ROP monitoring. This study objectively studies vascular features in live mice during development using noninvasive retinal imaging. METHODS Using fluorescein angiograp...

To cite: Mehrabi E, Khan K, Malik SA. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016217029 DESCRIPTION An infant exhibited weight faltering and failure to thrive after birth. She was born full term via an uncomplicated vaginal delivery to healthy, nonconsanguineous parents. The mother received prenatal care and standard screening tests were reportedly normal...

Baum, J. D. (1971). Archives of Disease in Childhood, 46, 247. Retinal artery tortuosity in ex-premature infants. 18-year follow-up on eyes of premature infants. Ophthalmic examinations have been performed on 52 expremature infants who had reached their late teens. These patients all weighed 1500 g or less at birth, and were born during a period of transition from liberal to restricted oxygen t...