background most patients with trauma experience different levels of pain. due to side effects as well as economic burden of drugs used for pain relief after trauma commonly, it is important to use low-cost methods independently or combined with drugs to alleviate pain. objectives therefore, this study aimed to investigate the effects of topical sesame oil on pain severity and frequency of recei...

One of the common chronic inflammatory skin diseases is Acne Vulgaris that affects up to 80% of a teen-age population. The progress of acne lesions is due to colonization of Propionibacterium acnes (P .acnes) in hair follicles. Treatment of acne includes topical or systemic therapy or combination therapy, with a tendency to perform topical therapy in mild to moderate acne. Nanoemulsions, small ...

BACKGROUND Limited evidence supports Nigella sativa's role as an effective complementary and alternative medicine and the anti-inflammatory effects of Nigella sativa on patients with allergic rhinitis. OBJECTIVE The aim of this study was to investigate the effect of topical application of Nigella sativa oil and oral acetaminophen on pain in the elderly with knee osteoarthritis residing in a p...

Sir, Besides traditional topical and systemic pharmacological treatments for the therapy of vulvovaginal yeast and bacterial infections, numerous over-the-counter medicaments containing natural substances (e.g. tea tree oil, echinacea, sodium caprylate, propolis) are marketed. Patients often prefer alternative medicine and selfprescribe herbal-based products. We report here an unusual case of a...

INTRODUCTION A water-in-oil microemulsion is a thermodynamically stable emulsion that has the capacity to 'hide' water-soluble molecules within a continuous oil phase. The very small size of the water droplets within the microemulsion means that these types of formulation can be applied topically to the skin, with the result that peptides and proteins can be delivered effectively into the derma...

PURPOSE To evaluate the effectiveness of topical 1% cyclosporine eye drops diluted in either of the two vehicles-olive and linseed oil-and that of the oils themselves in treating experimentally-induced keratoconjunctivitis sicca (KCS) in rabbits. METHODS KCS was induced in 25 New Zealand rabbits using 1% atropine sulfate eye drops for 7 days before treatment and throughout the treatment perio...

BACKGROUND Topical application of oils and oil-based formulations is common practice in skin care for both adults and infants. Only limited knowledge however is available regarding skin penetration and occlusive potential of oils and common methods for measuring skin moisturization fall short when it comes to the moisturizing effect of oils. OBJECTIVE In this study we used in vivo confocal Ra...

BACKGROUND Earwax is a common problem in both primary and secondary care. There is uncertainty as to the most effective topical treatment. AIM To assess the evidence concerning the efficacy of topical preparations used for treating earwax. DESIGN OF STUDY Systematic review and meta-analysis. METHOD Searching for randomised controlled trials (RCTs) of relevant studies. Classification of pr...

Objective-The objective of this study was to compare effects of olive oil and lime water combination with silver sulfadiazine in third-degree burn healing. Design-Randomized experimental study. Animals-Sixty-three adult male Bulb/C mice weighing25±5 gr. Procedures-The mice were anesthetized with an intraperitoneal injection of ketamine 10% and xylazine 2% combination and the t...

background: the prevalence of denture stomatitis has been shown to vary from 15 to 65% in complete denture wearers. satureja hortensis l. has been considered to have antinociceptive, antiinflammatory, antifungal and antimicrobial activities in vitro and exhibits strong inhibitory effect on the growth of periodontal bacteria. the aim of this study was to evaluate the efficacy of a 1% gel formula...