White piedra is a superficial fungal infection of the hair shaft, caused by Trichosporon beigelii . We report two cases of white piedra presenting as brown palpable nodules along the hair shaft with a fragility of scalp hairs. T. beigelii was demonstrated in hair culture of both the patients and T. ovoides as a species was confirmed on carbohydrate assimilation test. The first patient responded...

a 3-month-old male red fox that was in contact with a persian cat referred to the small animal hospital, faculty of veterinary medicine, university of tehran with multi-focal circular non-pruritic skin lesions and hair loss mainly on the head and extremities. a complete series of dermatologic tests such as wood’s light examination, direct microscopic examination, and fungal culture were perform...

Antifungal drug ketoconazole causes severe drug-drug interactions by influencing gene expression and catalytic activity of major drug-metabolizing enzyme cytochrome P450 CYP3A4. Ketoconazole is administered in the form of racemic mixture of two cis-enantiomers, i.e. (+)-ketoconazole and (-)-ketoconazole. Many enantiopure drugs were introduced to human pharmacotherapy in last two decades. In the...

Infections caused by bacteria and fungi resistant to antimicrobials are one of the main public health problems in world. These microorganisms associated with high rates morbidity mortality also hospital costs. Their emergence spread closely related excessive inappropriate use medical veterinary practices animal production. For treatment Candida spp. there few classes antifungals available for t...