The aim of this study was to prepare w/o Micro-emulsions naproxen for topical application & evaluate in vitro permeation Naproxen. On the basis ternary phase diagram and drug solubility test Tween-20, Oleic acid Polyethylene Glycol 400 selected these are eminently used as an appropriate transporting system introducing Naproxen transdermal delivery. physicochemical properties microemulsions ...

mainly into semisolid formulations such as ointment, cream and lotion and dermal patches such as pressure sensitive adhesive tapes and cataplasma. These topical formulations contain many kinds of pharmaceutical additives. Alcohols, glycols, l-menthol, mineral and vegetable oils and surfactants as well as polymeric additives are prescribed for skin penetration enhancers, drug solubilizers, drug ...

Topical medication delivery is the process of directly treating a cutaneous ailment or manifestation general disease by applying pharmaceutical dosage form to skin with goal reducing drug's pharmacological other effects surface skin. A wide range forms, such as semisolids, liquid preparations, sprays, solid powders, gels, creams, and ointments, are used in topical drug systems. gel cross-linked...