Background Solid organ transplantation (SOT) has emerged as an important lifesaving procedure for patients with a wide range of end-organ diseases characterized by dysfunction or specific function failure. SOT rejection is major complication requiring (pts) to undergo lifelong immunosuppression prevent allograft rejection. 1 Skin cancers (SCs) including cutaneous squamous cell carcinoma (CSCC) ...

T hierarchical, multidimensional assemblies of protein–DNA structures known as the eukaryotic chromosome present both challenges and opportunities for biophysicists interested in chromatin structure (1, 2). One of the most interesting aspects of chromatin structure to come to light in recent years is the discovery that the core histone proteins alone can effectively direct the formation of mult...

The Anthropocene has seen declining biodiversity inextricably linked to our societies, values, and choices. This requires ecologists engage with the public in ecosystems such as cities learn from help inform their values experiences regarding role urban nature. article presents a transdisciplinary citizen science project on spontaneous vegetation context of botany, art-science, participatory re...

The histone methyltransferase SETDB1 contributes to the silencing of local chromatin and the target specificity appears to be determined through various proteins that SETDB1 interacts with. This fundamental function endows SETDB1 with specialized roles in embryonic cells. Keeping the genomic and transcriptomic integrity via proviral silencing and maintaining the pluripotency by repressing the d...

There is a national trend for swine enterprises to increase in size due to cost efficiencies associated with economies of scale. This study was performed to evaluate the effect of farm size on manure application management for a survey o f 391 swine producers in Minnesota. There was a statistically significant effect of farm size on almost all of the variables evaluated. As farm size increased:...

Inference has long been the concern of assorted disciplines that vary in focus, rationale, apparatus, terminology, and achievement. There would appear an inverse proportion between the range and the orderliness of the knowledge accumulated by the various disciplines. Literary study tends to the first extreme, logic and its heritage in modern pragmatics to the second, either imbalance precluding...