Studies of adult BALB/c mice given total lymphoid irradiation (TLI; 3,400 rad) 1 have shown that both heterologous proteins and allogeneic bone marrow (BM) cells injected into irradiated mice evoke a state of tolerance rather than immunity (1). The ease of induction of tolerance to protein antigens appears to be related to the development of a population of T cells that can nonspecifically supp...

The thymidine labeling index (TLI) showed a lognormal dis tribution for 133 primary breast carcinomas with a median of 2.21 and a range of 0.04 to 18.6/100. High TLI's were associated significantly with nuclear anaplasia, pushing tumor border, necrosis, cellular inflammation, and total replacement of lymph nodes involved by tumor, and the data suggested an association of high TLI with large pri...

BACKGROUND Laser Doppler flowmetry (LDF) can be used to measure cerebral microcirculation in relation to stereotactic deep brain stimulation (DBS) implantations. OBJECTIVE To investigate the microcirculation and total light intensity (TLI) corresponding to tissue grayness in DBS target regions with high-resolution LDF recordings, and to define a resolution which enables detection of small ves...

We added spleen cells from adult BALB/c mice treated with total lymphoid irradiation (TLI) to the mixed leukocyte reaction (MLR) using a variety of responder and stimulator cells. The spleen cells nonspecifically suppressed the uptake of [3H]-thymidine and the generation of cytolytic cells regardless of the responder-stimulator combination used. We also examined the effect of the spleen cells o...

International Perspectives on Sexual and Reproductive Health 200 and demonstrated adequate model fit (RMSEA=0.06, CFI=0.96, TLI=0.97). For the second-order factor of the wife’s autonomy items, the standardized factor loadings of each dimension ranged from 0.4 to 0.9 (p<.001), and the overall model fit was adequate (RMSEA=0.06, CFI=0.94, TLI=0.96). For the husband’s inequitable gender attitudes ...

Shock is accompanied by generalised splanchnic hypoperfusion, and splanchnic organs like the pancreas can be damaged, as shown in animal experimental models and in humans, by the presence of high plasma concentrations of trypsin and other pancreatic enzymes. In order to design a radioimmunoassay technique (RIA) for the measurement of equine trypsin-like immunoreactivity (TLI) in biological flui...

Allogeneic bone marrow transplantation is a curative treatment for leukemia and lymphoma, but graft-vs-host disease (GVHD) remains a major complication. Using a GVHD protective nonmyeloablative conditioning regimen of total lymphoid irradiation and antithymocyte serum (TLI/ATS) in mice that has been recently adapted to clinical studies, we show that regulatory host NKT cells prevent the expansi...