The study evaluated the in vitro iron chelating, lipid peroxidation inhibitory and DNA protective activities of hydroalcoholic (60% ethanolic) extracts of various plant parts of Terminalia chebula, Caesalpinia crista, Cajanus cajan, Terminalia belerica, Emblica officinalis, and Tinospora cordifolia. The iron chelating property of the plants is in accordance with the order of their IC50 values f...

BACKGROUND Both experimental and clinical studies suggest that oxidative stress plays a major role in the pathogenesis of both types of diabetes mellitus. This oxidative stress leads to β-cell destruction by apoptosis. Hence exploring agents modulating oxidative stress is an effective strategy in the treatment of both Type I and Type II diabetes. Plants are a major source of anti-oxidants and e...

For thousands of years, plant based herbal medicines have been utilized by millions people all over the world. Plant materials or products are used in different folk/traditional medical systems, such as Chinese, African and Indian like Siddha, Ayurveda, Unani, Homeopathy. Tinospora cordifolia (TC) is a medicinal belonging to family Menispermaceae. It big deciduous, climbing shrub growing preval...

The genus Tinospora includes 34 species, in which several herbs were used as traditional medicines by indigenous groups throughout the tropical and subtropical parts of Asia, Africa, and Australia. The extensive literature survey revealed Tinospora species to be a group of important medicinal plants used for the ethnomedical treatment of colds, headaches, pharyngitis, fever, diarrhea, oral ulce...

Guduchi also known as having heart shaped leaves, belongs to family Menispermaceae native Indian subcontinent. The aqueous and methanol stem extract of is being used for their Immunomodulatory activity they revive immune imbalance which helps in preventing healing many diseases. intensively studied its immunomodulating effects because wide-ranging uses treating diseases related system indigenou...

The safety of Tinospora cordifolia and its potential to protect against ultraviolet radiation-induced cytotoxicity and DNA damage in PC12 cells were investigated. To evaluate the safety of T. cordifolia, cell viability and agarose gel electrophoresis were carried out using PC12 cells treated with 0 to 100 μg mL(-1) of methanol extract of T. cordifolia. T. cordifolia extracts did not show cytoto...

BACKGROUND The major damaging factor during and after the ischemic/hypoxic insult is the generation of free radicals, which leads to apoptosis, necrosis and ultimately cell death. Rubia cordifolia (RC), Fagonia cretica linn (FC) and Tinospora cordifolia (TC) have been reported to contain a wide variety of antioxidants and have been in use in the eastern system of medicine for various disorders....

Pharmacognosy Research,2022,14,3,289-296.DOI:10.5530/pres.14.3.42Published:July 2022Type:Original ArticleAuthors:Abhijeet Puri, and Swati Patil Author(s) affiliations:Abhijeet Puri*, Department of Pharmacognosy, Principal. K M Kundnani College Pharmacy, Cuffe Parade, Mumbai, Maharashtra, INDIA. Abstract:Background: According to a literature review Tinospora cordifolia possess alkaloids, tannins...

In our classical Ayurvedic texts, it has been described as beneficial in treating various types of diseases. Tinospora cordifolia satva (TCS) and ghana (TCG) is one the unique Ayuvedic preparations, prepared from aqueous extract Giloy (Tinospora Miers.) stem. These are frequently used medicines for treatment Madhumeha, Pandu, Kamala, Amlapitta, Grahani, Kustha, Jirna Jwara Viswamjwara, Trishna,...

Tinospora cordifolia (Willd.) Hook.f. & Thomson is a climbing deciduous shrub. It is found throughout tropical part of India also found in China, Bangladesh, Myanmar and Srilanka. Plant refers wide range of soil, acid to alkaline and it needs moderate moisture level. In Ayurveda, basically it is used for its general adaptogenic, rejuvenating and immunomodulatory activity. Besides of these prope...