BACKGROUND Lipomyelomeningocele (LMM) is a common and severe closed neural tube defect in children. Because of the complex anatomy of LMM and the difficulty in assessing the value of surgery, the management of patients with LMM is controversial. This study was undertaken to evaluate effective techniques and procedures in surgical treatment of LMM and to assess the value of early neurosurgical i...

The adult Central Nervous System (CNS) harbors neural progenitor cells (NPCs) in three areas: the subventricular zone (SVZ) of the lateral ventricles and the subgranular zone in the hippocampus and around the central canal in the spinal cord. The NPCs can be isolated and cultured in vitro. To improve recovery after a CNS trauma by using endogenous NPCs as well as by NPC transplantation, it is i...

Split cord malformation and fatty filum are completely different clinical entities and thought to arise via different pathophysiologies. Recognition of these distinct lesions in the same patient is important for appropriate diagnosis and management. A 3 year-old boy presented with skin lesions and mild leg weakness suggestive of spinal malformation. Magnetic resonance imaging revealed type II s...