Many long-term, follow-up studies have shown that steroids are effective in patients with myasthenia gravis (MG) who have undergone thymectomy. However, few long-term studies have documented the response of MG to steroids alone. We describe two patients who successfully resolved the symptoms of MG without myasthenic crisis or serious side effects by steroid treatment without thymectomy or other...

Fifty-four thymus glands removed surgically from patients with myasthenia gravis were examined using an accurate morphometric technique and the data compared with the response to thymectomy. There is a tendency for patients with relatively unreactive thymus glands to obtain a better result from thymectomy but this is not statistically significant.

The thymus plays an important role in the development of the immune cell pool; it serves as the primary location for T-lymphocyte maturation. Early cardiac surgical interventions for congenital heart defects are necessarily associated with thymectomy, i.e. the partial or complete removal of the thymus. A newborn infant already has a functioning thymus and developed cells of the immune system. H...

Introduction:yasthenia gravis is an autoimmune disorder resulting from a decreased number of active acetylcholine receptors at the neuromuscular junction. Thymectomy is one of its current treatments. Due to sensitivity of myasthenic patients to non-depolarizing muscle relaxants and also the interaction of this medication with anti-cholinestrase drugs, determining the dosage of non-depolarizing ...

Myasthenia gravis (MG) is an autoimmune disease mediated by auto-antibodies against the neuromuscular junction. The thymus has an important role in the pathogenesis of MG because most of the patients have thymic pathology and thymectomy (TE) can reduce the severity of the disease. In the present study, the frequency of Th17 and Tc17 cells were studied in MG patients (pre and 6 months post-TE) a...

BACKGROUND Central lymph node dissection (CND) has been proposed in the treatment of patients affected by papillary thyroid cancer (PTC) with clinically negative neck lymph nodes. The procedure allows pathologic staging of lymph nodes of the central compartment and treatment of the micrometastases. By comparing bilateral and unilateral thymectomy during total thyroidectomy with central lymph no...

INTRODUCTION Systemic lupus erythematosus (SLE) and myasthenia gravis (MG) are autoimmune diseases that show some similarities: a higher incidence in young women, relapsing-remitting course and positive anti-nuclear antibodies (ANA). However, they are two different clinical syndromes, which can coexist or precede each other. Thymectomy is a therapeutic option for patients with severe MG or thym...

Background: Myasthenia gravis is an autoimmune disease characterized by weakness and fatigue of voluntary muscles. Thymectomy is considered an effective therapeutic option for patients with myasthenia gravis. The purpose of this study is to evaluate the efficacy of thymectomy by partial sternotomy for the treatment of non-thymomatous myasthenia gravis. Materials and Methods: From 2002 to 2006, ...

OBJECTIVE Myasthenia Gravis is a neuromuscular disorder characterized by weakness and fatigability of skeletal muscles. Thymectomy is now beneficial even for non-thymomatous patients. The aim of this paper is to evaluate the role of thymectomy as on the treatment options for myasthenia gravis. METHODS Thirty patients underwent thymectomy in the period from April 1999 through to July 2000. The...