Introduction. Thioctic (α-lipoic) acid is an endogenous antioxidant and used for liver diseases, poisoning with salts of heavy metals, hyperlipidemia, atherosclerotic heart disease, neuropathy, insulin-resistant forms diabetes mellitus, etc. technologies producing tableted medicinal preparations thioctic acid, necessary the pharmaceutical development tablets at industry enterprises. Text. The r...

Alpha lipoic acid (ALA, thioctic acid), among other actions, is an essential coenzyme in the conversion of pyruvate to acetyl co-enzyme A. Therefore, it is necessary for the production of energy for aerobic organisms. Scientists have found that it can be used medically to help regenerate liver tissue, reverse the complications of diabetes mellitus, slow or stop the growth of cancer cells, and c...

α-lipoate also known as thioctic acid, 1,2-dithiolane-3-pentanoic acid, 1,2-dithiolane-3-valeric acid or 6,8-thioctic acid has generated considerable clinical interest as a thiol-replenishing and redoxmodulating agent [16–18,27]. Lipoate has been used for a long time in Germany to treat complications associated with diabetes [11]. Recently, lipoate has also been introduced to the United States ...

Alpha lipoic acid, or just lipoic acid (LA), is a unique and potent antioxidant. It can deliver antioxidant activity in both fatand water-soluble mediums, and it is capable of having an antioxidant effect in both its oxidized (LA) and reduced (DHLA [dihydrolipoic acid]) forms (Goraca et al., 2011). This effectively allows LA to deliver its antioxidant effect to any cell or tissue type, as well ...

BACKGROUND Quantum dots (QDs) are crystalline nanoparticles that are compatible with biological systems to provide a chemically and photochemically stable fluorescent label. New ligand probes with fluorescent reporter groups are needed for detection and characterization of G protein-coupled receptors (GPCRs). RESULTS Synthetic strategies for coupling the A2A adenosine receptor (AR) agonist CG...