despite development of new approaches for the treatment of cancer disease, it is the second cause of mortality in world. annually, 30000 persons die in iran due to cancer diseases. eighty percent of cancer patients are children which about 50% children lead to death. given the high rate of cancer-related death, the new approaches for prevention, control, early diagnosis, and treatment of this d...

Hematophagous animals including leeches have been known to possess biologically active compounds in their secretions, especially in their saliva. The blood-sucking annelids, leeches have been used for therapeutic purposes since the beginning of civilization. Ancient Egyptian, Indian, Greek and Arab physicians used leeches for a wide range of diseases starting from the conventional use for bleed...

The treatment of the peptic ulcer disease involves several options. The present discussion deals with the long-term management with emphasis on the application of vagotomy. Eradication of Helicobacter pylori is the treatment of choice in ordinary peptic ulcer patients. Exceptions are non-steroidal, anti-inflammatory drug-induced ulcers and the Zollinger-Ellison syndrome. Failures to eradicate H...

Hydrogels have been used for biomedical applications in recent decades. They are a perfect candidate for regenerative medicine as they resemble the extracellular matrix of native tissues. In addition, their highly hydrated structure makes them a suitable choice for drug and other therapeutics delivery. Injectable hydrogels have increasingly gained attention due to their capability for homogeneo...

Conventional transdermal drug delivery systems (TDDS) have been designed for drug delivery through the skin. These systems use the permeability property of stratum corneum, the outermost surface layer of the skin. Applying polymeric micro and nanofibers in drug delivery has recently attracted great attention and the electrospinning technique is the preferred method for polymeric micro-nanofiber...