نتایج جستجو برای: the scl

تعداد نتایج: 16053474  

2017
M. S. Kavitha

Design for testability (DFT) refers to hardware design styles or it is an added hardware that reduces test generation complexity and test cost, also increases test quality. Sleep Convention Logic (SCL) is an asynchronous logic style which is based on Null Convention Logic (NCL). In the SCL the combinational blocks are made of threshold gates. SCL utilizes power gating method to further reduce t...

Journal: :Investigative ophthalmology & visual science 2012
Osama M A Ibrahim Takashi Kojima Tais Hitomi Wakamatsu Murat Dogru Yukihiro Matsumoto Yoko Ogawa Junko Ogawa Kazuno Negishi Jun Shimazaki Yasuo Sakamoto Hiroshi Sasaki Kazuo Tsubota

PURPOSE To investigate the lipid and DNA oxidative stress as well as corneal and retinal effects after ultraviolet B (UV-B) exposure in mice, with or without silicon hydrogel soft contact lenses (SCL). METHODS Twenty-eight C57BL6-strain male mice were divided into four groups: group I, control group with no SCL (SCL [-]) and no UV-B exposure (UV-B [-]); group II, senofilcon A SCL (senofilcon ...

2009
Songbo Tan Xueqi Cheng

In recent years, Structural Correspondence Learning (SCL) is becoming one of the most promising techniques for sentiment-transfer learning. However, SCL model treats each feature as well as each instance by an equivalent-weight strategy. To address the two issues effectively, we proposed a weighted SCL model (W-SCL), which weights the features as well as the instances. More specifically, W-SCL ...

2014
JOEL LOUWSMA

This paper has two parts, on Baumslag–Solitar groups and on general G–trees. In the first part we establish bounds for stable commutator length (scl) in Baumslag–Solitar groups. For a certain class of elements, we further show that scl is computable and takes rational values. We also determine exactly which of these elements admit extremal surfaces. In the second part we establish a universal l...

2001
David S. Chervinsky Du H. Lam Michael P. Melman Kenneth W. Gross Peter D. Aplan

SCL and LMO1 were both discovered by virtue of their activation by chromosomal translocation in patients with T-cell acute lymphoblastic leukemia (T-ALL). Overexpression of SCL and LMO1 in the thymus of transgenic mice leads to T-ALL at a young age. scid (severe combined immunodeficient) mice are unable to efficiently recombine antigen receptor genes and consequently display a developmental blo...

Journal: :Bone 2017
David G Little Lauren Peacock Kathy Mikulec Michaela Kneissel Ina Kramer Tegan L Cheng Aaron Schindeler Craig Munns

In this study, we examined the therapeutic potential of anti-Sclerostin Antibody (Scl-Ab) and bisphosphonate treatments for the bone fragility disorder Osteogenesis Imperfecta (OI). Mice with the Amish OI mutation (Col1a2 G610C mice) and control wild type littermates (WT) were treated from week 5 to week 9 of life with (1) saline (control), (2) zoledronic acid given 0.025mg/kg s.c. weekly (ZA),...

Journal: :Blood 2007
Lucy J Patterson Martin Gering Craig E Eckfeldt Anthony R Green Catherine M Verfaillie Stephen C Ekker Roger Patient

The transcription factors Scl and Lmo2 are crucial for development of all blood. An important early requirement for Scl in endothelial development has also been revealed recently in zebrafish embryos, supporting previous findings in scl(-/-) embryoid bodies. Scl depletion culminates most notably in failure of dorsal aorta formation, potentially revealing a role in the formation of hemogenic end...

Journal: :Arthritis Research & Therapy 2007
Geurt Schilders Reinout Raijmakers Kelen CR Malmegrim Lieselotte Vande Walle Xavier Saelens Wilma Vree Egberts Walther J van Venrooij Peter Vandenabeele Ger JM Pruijn

Recent studies have implicated the dying cell as a potential reservoir of modified autoantigens that might initiate and drive systemic autoimmunity in susceptible hosts. A number of subunits of the exosome, a complex of 3'-->5' exoribonucleases that functions in a variety of cellular processes, are recognized by the so-called anti-PM/Scl autoantibodies, found predominantly in patients suffering...

Journal: :The Journal of clinical investigation 1985
W J van Venrooij S O Stapel H Houben W J Habets C G Kallenberg E Penner L B van de Putte

More than 300 sera from patients with a connective tissue disease were analyzed with the immunoblotting technique. The presence of autoantibodies against an 86,000-mol wt marker antigen for diffuse scleroderma (Scl-86) was found in 14 out of 33 patients with scleroderma. The presence of anti-Scl-86 antibodies seemed to correlate with the diagnosis of diffuse scleroderma since they were found in...

Journal: :Blood 2005
Thorsten M Schlaeger Hanna K A Mikkola Christos Gekas Hildur B Helgadottir Stuart H Orkin

The stem-cell leukemia gene (SCL/tal1) is essential for the formation of all blood lineages. SCL is first expressed in mesodermal cells that give rise to embryonic blood cells, and continues to be expressed in fetal and adult hematopoietic stem cells (HSCs). However, SCL is not required for the maintenance of established long-term repopulating (LTR) HSCs in the adult. The time point at which HS...

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