BACKGROUND Although elective single embryo transfer (eSET) minimizes the multiple birth rate after in vitro fertilization (IVF)/intra cytoplasmic sperm injection (ICSI), there remain concerns in many countries that it is less effective and more expensive than conventional double embryo transfer (DET). METHODS We compared the clinical outcome achieved in the years 1995-1999, in which eSET was ...

STUDY QUESTION Do the reproductive outcomes from the transfer of fully hatched (FH) blastocysts differ from those of not fully hatched (NFH) blastocysts? SUMMARY ANSWER Biochemical pregnancy rate (BPR), implantation rate (IR), live birth rate (LBR) and early pregnancy loss (EPL) rate are similar in FH and NFH single euploid blastocyst embryo transfers. WHAT IS KNOWN ALREADY The use of exten...

BACKGROUND There is no consensus on the exact parameters that define the LH surge for natural cycle frozen-thawed embryo transfers (NC-FET). Accurately determining the LH surge would affect the timing, and subsequently the success rates, of embryo transfer. Therefore, the aim of this study was to delineate the optimal levels and relationship for luteinizing hormone (LH) and estradiol in an effo...

Objective: To investigate the correlation of blood flow detected by 2-Dimensional Power Doppler (2D-PD) sonography in the subendometrial-endometrial unit with the pregnancy outcome in frozen-thawed embryo transfer (FET) cycles. Study design: Prospective non-randomized observational study. Materials and methods: A total of 127 patients undergoing their first FET cycle were recruited and prepared...

BACKGROUND Embryo transfer to a developed endometrium is an important prognostic factor in frozen-thawed embryo transfer cycle outcome. Vaginal estrogen, such as Vagifem vaginal tablets and Premarin vaginal cream, is a regimen used for the patients with refractive endometria. OBJECTIVE Our objective was to compare the effects of Vagifem and Premarin on the endometrial thickness of the patient...

BACKGROUND The extremes of BMI are associated with an increased risk of miscarriage both in spontaneously conceived pregnancies and after fertility treatment. The aim of the present study was to study the effect of BMI on miscarriage rate (MR) in fresh IVF/ICSI, and in spontaneous and hormonally substituted frozen-thawed embryo (FET) cycles. METHODS Analysis was carried out on 3330 first preg...

BACKGROUND Polycystic ovary syndrome (PCOS) patients are at increased risk of pregnancy complications, which may impair pregnancy outcome. Transfer of fresh embryos after superovulation may lead to abnormal implantation and placentation and further increase risk for pregnancy loss and complications. Some preliminary data suggest that elective embryo cryopreservation followed by frozen-thawed em...

The aim of this study was to analyze whether GnRH agonist treatment before frozen-thawed embryo transfer (FET) improved the pregnancy outcomes of adenomyosis patients and to study the effects of GnRH agonists to the health of offspring. This study was a retrospective analysis of 139 patients who underwent in vitro fertilization/ intracytoplasmic sperm injection (IVF/ICSI) between Jan 2011 and D...

EFFICACY OF INTRAUTERINE INSTILLATION AUTOLOGOUS PLATELET-RICH PLASMA ON ENDOMETRIAL GROWTH DURING THE FROZEN-THAWED EMBRYO TRANSFER CYCLES