We previously reported that the time-dependent relative changes of transepithelial electrical resistance (TEER) after exposing four different chemicals to a human corneal epithelium (HCE) model were well correlated to the potential of ocular irritancy. Meanwhile, we recently developed a collagen vitrigel membrane (CVM) chamber possessing a scaffold composed of high-density collagen fibrils equi...

Researchers occasionally have to work with an extremely small sample size, defined herein as N ≤ 5. Some methodologists have cautioned against using the t-test when the sample size is extremely small, whereas others have suggested that using the t-test is feasible in such a case. The present simulation study estimated the Type I error rate and statistical power of the oneand two-sample ttests f...

In order to ensure software performance as well as software quality, various testing techniques have been used to detect faults as early and as many as possible during the development phase. Over the last decade, the size and complexity of software developed have increased tremendously. Highly customizable software allow users to configure the software to the users’ needs, however, if not teste...

tuberculosis is an important opportunistic disease among hiv- infected persons worldwide; from march 1999 to feburery 2001 we had seventeen patients with hiv-infection and tuberculosis. here we are presenting the clinical manifestations, diagnosis, treatment and outcome of them. all of them were male, 11 patients had pulmonary and 5 patients had extrapulmonary (pleural effusion 1, hepatic granu...