Computer assisted surgical planning and image guided technology have become increasingly used in neurosurgery. We have developed a system based on ATmC (Adaptive Template moderated Classification) for the automated segmentation of 3D MRI brain data sets of patients with brain tumors (meningiomas and low grade gliomas) into the skin, the brain, the ventricles and the tumor. In a validation study...

Highly ordered mesoporous graphitic carbon was synthesized from a simple surfactant-assisted nanocasting route, in which ordered mesoporous silica SBA-15 maintaining its triblock copolymer surfactant was used as a hard template and natural soybean oil (SBO) as a carbon precursor. The hydrophobic domain of the surfactant assisted SBO in infiltration into the template's mesoporous channels. After...

Ordinarily, the electrospinning process generates one-dimensional fibers which assemble into nonwoven membrane structures due to instabilities in the fluid jet. In this paper, an electrospinning procedure is developed that utilizes patterned collectors to produce aligned membranes with designed topological structures. The template-assisted electrospinning approach is demonstrated using polycapr...

OBJECTIVE To explore the therapeutic value of 3-D printing template-assisted 125I-seed implantation in the treatment of malignant liver tumors. MATERIALS AND METHODS Fifteen liver cancer patients with 47 total lesions were treated with 3-D printing template-assisted radioactive seed implantation (group A), and 25 liver-tumor patients with 66 total lesions were treated with 125I-seed implantat...

The ultimate goal in protein de novo design is the Construction of artificial proteins exhibiting tailor-made structural and functional properties. To create nativelike macromolecules in copying nature's way has proven to be difficult because the mechanism of folding in its complexity has yet to be unravelled. In the present review we describe a conceptually different approach in protein design...