Systemic exacerbation of allergic responses, in which mast cells play a critical role, results in life-threatening anaphylactic shock. Sphingosine-1-phosphate (S1P), a ligand for a family of G protein-coupled receptors, is a new addition to the repertoire of bioactive lipids secreted by activated mast cells. Yet little is known of its role in human mast cell functions and in anaphylaxis. We sho...

purpose: the aim of this research is to study the relationship between the co-authorship and the impact factor in persian technical and engineering journals of iran during the years 2001-2010. method: the research method is analytic-descriptive with a citation analysis approach.  the research population consists of 9321 papers from 77 persian technical and engineering journals of iran during th...

Masih rendahnya pemanfaatan buku KIA masih terkendala oleh pengetahuan dan sikap ibu tentang manfaat dari sebagian juga menganggap hal-hal yang berhubungan dengan hanya sekedar catatan pemeriksaan (Yayu, dkk,2015).4 Tujuan penelitian ini adalah untuk mengetahui gambaran Buku Kesehatan Ibu Anak (KIA) di Kelurahan Wanasari Rw.013 Kabupaten Bekasi tahun 2020. Variabel independen nya variabel depen...

Introduction Although the therapy for Behçet’s disease (BD) has improved since infliximab was approved for refractory retinochoroiditis therapy in Japan, the exact pathogenesis of BD remains unclear. Our recent genome-wide association study has identified the IL10 and IL23RIL12RB2 loci as susceptibility genes for BD, in addition to HLA-A*26 and B*51. rs1495965 is located in the intergenic regio...

Several neurodegenerative diseases are linked to defects in brain cholesterol metabolism. The brain comprises only ~6% of total body weight but contains 25% of cholesterol in the body. Unlike phospholipids, which are synthesized in both cell bodies and axons of neurons, cholesterol synthesis is restricted to cell bodies. Thus, efficient mechanisms exist for delivery of cholesterol to axons for ...

the aim of the present research was to compare the performance evaluation indicators of club coaches from experts, athletes and coaches' viewpoints. the statistical population included all physical education experts of guilan province, heads, deputy heads and secretaries of physical education boards, athletes and coaches from rasht city (n=470) and 345 subjects (73.4%) participated in the ...