Technetium-99m MAG3, a technetium-labeled analog of hippuran, was compared with [131I] hippuran using a simultaneous dual isotope study in 20 patients. The plasma clearance for MAG3 was lower than that of hippuran, but its plasma concentration was higher, resulting in similar rates of excretion and similar renal time-activity curves. Apart from better statistics with the technetium-labeled agen...

greatly facilitated by technetium-99m (99mTc)tracers, having comparable avid uptake and prolonged reten tion in the brain as the iodine-123-('231) labeled amines, isopropylamphetamine (IMP) and hydroxy benzyl-propanediamine (HIPDM). Such molecules would facilitate cerebral blood flow (CBF) tomography by conventional single photon emission computed to mography (SPECT). Technetium-99m is inexpens...

the high expression of somatostatin receptors in many tumours, have made receptor scintigraphy with 111in-dtpa-octreotide a widly used procedure in nuclear medicine. despite its clinical success, some limitation and drawbacks of radiolabelling with 111in remain, especially those concerned with the cost, availability and physical decay properties of this radionuclide. 99mtc-edda/hynic-tyr3-toc w...

Pentavalent technetium-99m dimercaptosuccinic acid ((99m)Tc-(V)DMSA) is a tumor-seeking agent which was introduced to evaluate, image, and manage many types of cancers. In this review, the beginning of, and the most recent applications of using this agent was appraised. The relation with tumor cell detection and proliferation was reported and several mechanisms of uptake of (99m)Tc-(V)DMSA in t...

Abstract Background Mesenchymal stem cell treatments in dogs have been investigated as a potential innovative alternative to current conventional therapies for variety of conditions. So far, the precise mode action MSCs has yet be determined. The aim this study was gain more insights into pharmacokinetics by evaluating their biodistribution healthy after different injection routes. Methods Thre...

AIM The aim of this study was to assess the degree of alterations of renal function by using 99m-technetium dimercaptosuccinic acid ((99m)Tc-DMSA) and 99m-technetium diethylenetriaminepentaacetic acid ((99m)Tc-DTPA) scintigraphy in spinal cord injury (SCI) patients. MATERIAL AND METHODS Twenty-two consecutive SCI (15 paraplegic and 7 tetraplegic) patients (mean age: 49.1±13.4 years) who had n...

Tannic acid is a polyphenolic compound that could be labeled with technetium-99m. To produce about 90% yield of  (99m)Tc-tannic acid in acidic media (pH), the conditions required were 150 μg tin chloride, 30 min reaction time, and 200 μg of the substrate. (99m)Tc-tannic was stable for 6 h. Oral biodistribution of (99m)Tc-tannic showed that it concentrated in the stomach ulcer to reach about 50%...

The authors present a case of subhyoid ectopic thyroid with mediolateral location diagnosed by technetium-99m pertechnetate scan. The ectopia was associated with hypothyroidism and developmental retardation.

Gastrointestinal duplication cysts are a rare congenital malformation in the gastrointestinal tract, most commonly seen ilium. The present study reported child with mid ileal cyst ofthe ectopic gastric mucosa that was diagnosed by Technetium-99m pertechnetate single-photon emission computed tomography-computed tomography (SPECT-CT) scintigraphy. can massive lower bleeding early childhood (Mecke...

We present a patient with left-sided obstructed megaureter secondary to neuropathic bladder. He was referred for technetium-99m dimercaptosuccinic acid ((99m)Tc-DMSA) renal cortical scintigraphy to evaluate renal cortical function. Images obtained 4 hr after injection showed significant activity in the dilated left ureter. When the ureter is visualized on DMSA scan, obstructive megaureter shoul...