Technetium is a long-lived (Tc: 213,000 year half-life) fission product found in nuclear waste and is one of the important isotopes of environmental concern. The known chemistry of technetium suggests that it should be found as pertechnetate, TcO4, in the extremely basic environment of the nuclear waste tanks at the Hanford site. However, other chemical forms of technetium are present in signif...

Ginkgo biloba extract (EGb) is a phytotherapeutic agent used for the treatment of ischemic and neurological disorders. Because the action of this important extract is not fully known, assays using different biological systems need to be performed. Red blood cells (RBC) are labeled with technetium-99m (Tc-99m) and used in nuclear medicine. The labeling depends on a reducing agent, usually stanno...

Introduction: Nowadays, nuclear medicine (NM) imaging indications in medical practice is raising. A practical step to get closer to the optimization rule is collecting data about patients’ exposure and definition of guidance levels. The aim of this study was definition of local reference level in Isfahan city. Materials and Methods: Questionnaires were given...

Poorly differentiated insular thyroid carcinoma is classified as a separate entity among other tumors of the thyroid gland. Its histological pattern and clinical course are regarded as intermediate between well-differentiated and anaplastic thyroid cancer. The authors report Tc-99m pertechnetate, Tc-99m MDP and radioiodine imaging features in a 33-year-old male patient with metastatic insular c...

1 Fadime Demir1, Taner Erselcan2, Bülent Turgut3, Zekiye Hasbek3, Perihan Kelkit4, Ayşegül Özdal5, Serdar Savaş Gül6, Pelin Duman7 1Department of Nüclear Medicine, Elazığ Researc and Educational Hospital, Elazığ, 2Nüclear Medicine, Muğla Sıtkı Koçman University, Faculty of Medicine, Muğla, 3Nüclear Medicine, Cumhuriyet University, Faculty of Medicine, Sivas, 4Department of Nüclear Medicine, Siv...

Alimentary tract duplications are uncommon congenital anomalies. Although most are symptomatic by the age of 2 years, some remain asymptomatic until adulthood. In one third of all cases, heterotopic gastric mucosa lines the wall of dupli­ cation, and may cause peptic ulceration, gastrointestinal bleed­ ing, fistulization or perforation. We report in this paper, a case of jejunoileal duplication...

This article examines the production of metastable technetium-99 (Tc-99m), the world’s most important radiopharmaceutical, focusing on reliability of supply and risks of nuclear terrorism. Only four producers manufactured about 95 percent of the world’s Tc-99m; a closure of any of them could cause worldwide shortfalls. Moreover, all four employ highly enriched uranium in their production proces...

The uptake of Tc-99m pertechnetate and Co-57 bleomycin and the ultrastructure of small blood vessels were studied in 10 cases of meningioma. When thin sections of 120 contact areas between adjacent endothelial cells were examined, 92% of the intercellular contacts contained one to three punctate tight junctions. Freeze fracture preparations revealed fascia occludens with one to four sealing str...

A 64-year-old man presented with clinical unilateral thyroiditis after chronic left neck trauma from his car seat belt. Thyroid function tests were normal. The initial thyroid Tc-99m pertechnetate scan demonstrated decreased uptake in the entire left lobe of the thyroid. The follow-up scan 1 month later showed a more normal uptake in the left lobe. This patient's clinical course, laboratory val...