نتایج جستجو برای: tc maa

تعداد نتایج: 30801  

Journal: :Rheumatology 2017
Ted R Mikuls Michael J Duryee Rafid Rahman Daniel R Anderson Harlan R Sayles Andrew Hollins Kaleb Michaud Frederick Wolfe Geoffrey E Thiele Jeremy Sokolove William H Robinson Nithya Lingampalli Anthony P Nicholas Geoffrey A Talmon Kaihong Su Matthew C Zimmerman Lynell W Klassen Geoffrey M Thiele

Objective To characterize the expression of malondialdehdye-acetaldehyde (MAA) adducts and anti-MAA antibody in articular tissues and serum of patients with RA. Methods Paired sera and SF were examined from 29 RA and 13 OA patients. Anti-MAA antibody, RF, ACPA and total immunoglobulin were quantified. SF-serum measures were compared within and between disease groups. The presence and co-local...

Journal: :Cancer research 1984
P Giacomini F Veglia P Cordiali Fei T Rehle P G Natali S Ferrone

Utilizing double-determinant immunoassays (DDIAs), the high-molecular-weight melanoma-associated antigen (HMW-MAA) was detected only in fetal skin and in one nipple of 54 normal tissues from adults tested, while the cytoplasmic MAA recognized by the monoclonal antibody 465. 12S was found in most of the normal tissues tested. Among malignant lesions, the HMW-MAA was found in melanomas, astrocyto...

Journal: :Journal of immunology 2006
Liaomin Peng Eric Ko Wei Luo Xinhui Wang Protul A Shrikant Soldano Ferrone

The human high m.w.-melanoma-associated Ag (HMW-MAA) is an attractive target for the immunotherapy of melanoma, due to its relatively high expression in a high percentage of melanoma lesions and its restricted distribution in normal tissues. Active immunization with HMW-MAA mimics has been previously shown to induce a HMW-MAA-specific, T cell-dependent Ab response associated with an apparent cl...

Journal: :The Journal of biological chemistry 2009
Purushottam Jha Balasubramanian Manickam Bharati Matta Puran S Bora Nalini S Bora

This study was initiated to induce experimental autoimmune anterior uveitis (EAAU) in Lewis rats by melanin-associated antigen (MAA; 22-kDa fragment of type I collagen alpha2 chain) derived from rat iris and ciliary body (CB), to localize MAA within the eye, and to investigate the possible mechanism of MAA generation in vivo. The EAAU model replicates idiopathic human anterior uveitis. Lewis ra...

Journal: :Cancer research 1991
P Chattopadhyay S V Kaveri N Byars J Starkey S Ferrone S Raychaudhuri

The mouse anti-idiotype (anti-id) monoclonal antibody (mAb) IMel-1 recognizes an idiotope in the antigen combining site of the immunizing anti-human high molecular weight melanoma-associated antigen (HMW-MAA) mAb 225.28. The mAb IMel-1 is able to induce an immune response against self cross-reacting HMW-MAA in rabbits that express HMW-MAA in normal tissues. Most of the rabbit anti-anti-id antib...

2011
Gargi Bagchi Yijing Zhang Kerri A Stanley David J Waxman

BACKGROUND Optimal androgen signaling is critical for testicular development and spermatogenesis. Methoxyacetic acid (MAA), the primary active metabolite of the industrial chemical ethylene glycol monomethyl ether, disrupts spermatogenesis and causes testicular atrophy. Transcriptional trans-activation studies have indicated that MAA can enhance androgen receptor activity, however, whether MAA ...

Journal: :The journal of physical chemistry. C, Nanomaterials and interfaces 2007
Yu-San Liu Yinghua Sun P Thomas Vernier Chi-Hui Liang Suet Ying Christin Chong Martin A Gundersen

The photoluminescence of mercaptoacetic acid (MAA)-capped CdSe/ZnSe/ZnS semiconductor nanocrystal quantum dots (QDs) in SKOV-3 human ovarian cancer cells is pH-dependent, suggesting applications in which QDs serve as intracellular pH sensors. In both fixed and living cells the fluorescence intensity of intracellular MAA-capped QDs (MAA QDs) increases monotonically with increasing pH. The electr...

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