nanocomposite composed of organoclay(cloisite 20a-c20a) and poly lactic acid (pla) was prepared by solvent casting method. physical, mechanical, thermal, barrier and microstructure properties of the composite were studied. x-ray diffraction (xrd) patterns and scanning electron microscopy (sem) images revealed that the diffraction peak of nanoclay shifted to lower angles and the d-spacing betwee...

we studied the antioxidant activities of the essential oils of zataria multiflora boiss. (zeo) and bunium persicum (boiss.) b. fedtsch (beo) in mixed form on linseed oil using (dpph•), ­(­abts•+), h2o2 scavenging, and reducing power assays. after calculation of ic50 for zeo and beo separately, interactions of the essential oils were investigated at the form of mixture and the results were given...

UNLABELLED Although increased fetal hemoglobin (HbF) levels have proven benefit for people with β-hemoglobinopathies, all current HbF-inducing agents have limitations. We previously reported that drugs that activate the NRF2 antioxidant response signaling pathway increase HbF in primary human erythroid cells. In an attempt to increase HbF levels achieved with NRF2 activators, in the present stu...

Arsenic is widely spread in our living environment and imposes a big challenge on human health worldwide. Arsenic damages biological systems through multiple mechanisms including the generation of reactive oxygen species. The transcription factor Nrf2 regulates the cellular antioxidant response that protects cells from various insults. In this study, the protective role of Nrf2 in arsenic toxic...

background: platanus species are widely cultured around the world and considered an important cause of allergic reactions. in the present study, we developed a sandwich elisa to quantify pla or 3 allergen in p. orientalis pollen extracts grown near high-traffic roads and compared it to pollen extracts collected from rural areas as control. methods: pollen samples were collected from three pollu...

physical, mechanical and structural properties of poly(lactic acid) (pla)-basedfilms containing different amounts of nanoclay and cellulose prepared bysolvent casting method were examined. physical properties including thickness,transparency and color did not change significantly with addition of nanoparticles to the polymer matrix. x-ray diffraction (xrd) patterns showed that pure pla has a se...

Three extraction parameters including time, material to solvent ratio, and temperature for the yield of Phyllanthus urinaria polysaccharides were optimized by response surface methodology. The results revealed that optimal process was time 5.3 h, 93 °C, ratio 1:47 g/mL, under which polysaccharide 6.40%; three had significant effect on yield, influence greatest lowest. antioxidant activity test ...

Objective(s): Application of eco-friendly materials like poly lactic acid (PLA) is increasing, to reduce environmental pollutions. In this research, the effect of silicon dioxide 1%, 3% and 5% nanoparticles on morphological, mechanical and chemicals interaction (FTIR) of PLA film was studied. Materials and Methods: Scanning electron microscope (SEM) was used, ...

The co-crystal of HA X-31 and a promising small molecule inhibitor, tert-butyl hydroquinone (TBHQ) 1 , was solved back in 2008 (PDBID: 3EYM) 8. Visual inspection of the 3EYM's TBHQ binding pocket via Chimera 7 reaffirmed TBHQ's drug-like potential and the interactions noted in Russel et al. The structural differences between Group 1 and Group 2 HA were confirmed using the matchmaker function pr...

Binding of the transcription factor nuclear factor E2-related factor 2 (Nrf2) to the antioxidant response element (ARE) in neural cells results in the induction of a battery of genes that can coordinate a protective response against a variety of oxidative stressors. In this study, tert-butylhydroquinone (tBHQ) and sulforaphane were used as activators of this pathway. Consistent with previous st...