Thai bitter gourd fruits (Momordica charantia Linn., TBG) has been previously demonstrated to possess phase II detoxificating enzymes inducing properties, as well as the ability to reduce phase I carcinogen activating enzyme activity in rat liver. In addition, it was partially inhibited 7,12-dimethylbenz(a)anthracene (DMBA)- induced mammary gland carcinogenesis in female Sprague-Dawley rats. In...

In the present study, an experimental investigation was conducted to characterize the unsteady vortices and turbulent flow structures around twin-box-girder (TBG) bridge deck models with and without cross beams. While the oncoming wind speed was fixed at U11⁄48.0 m/s (i.e., the corresponding Reynolds number, Re1⁄4 1:01 10, based on the height of the box girder) during the experiments, the gap w...

A patient is described in whom thyroid binding globulin (TBG) excess was found in association with a pituitary macroadenoma containing thyroid stimulating hormone (TSH)-producing cells, and the potential for diagnostic confusion arising from this unusual combination of endocrine disorders is discussed. The patient presented with visual field disturbance, and magnetic resonance imaging led to th...

Four patients are described who had a significant elevation of serum thyroxine-binding globulin (TBG). Review of these patients indicated that inappropriate therapy for thyrotoxicosis had been given in three cases. A study of our laboratory records revealed that significant TBG elevation was a relatively common phenomenon which occurred in approximately 0.45% of our hospital population. Patient...

A simple method is described for the simultaneous determinations of thyroxine and the effective thyroxine ratio (ETR) using a single kit of Thyopac-4. Thyopac ETR values obtained were 1.00 +/- 0.03 for normal subjects; 1.22 +/- 0.11 for hyperthyroid; 0.87 +/- 0.04 for hypothyroid; and 1.02 +/- 0.05 for pregnant women. Cases with TBG deficiency and the nephrotic syndrome indicated normal values....

Several investigations have reported an increase, in stored serum, in apparent thyroxine (T4) concentration measured by competitive binding radioassay (CPBR) with thyroxine-binding globulin (TBG) as the binding reagent [l-7]. Watson and Lees [4] attributed this increase to the production of a “mimic T4” during storage. Recently, we [6] and Rootwelt [7], working independently, discovered that th...

Antarctic residence (AR) is associated with a 50% increase in the thyrotropin (TSH) response to TSH-releasing hormone (TRH) and an expanded triiodothyronine (T3) distribution volume and extravascular hormone pool, collectively called the polar T3 syndrome. To investigate the possible biologic significance of this syndrome, we studied the relationship between nonstimulated TSH and serum lipid pr...

Chemical blockers used to displace thyronine analog from albumin in analog kits for assay of free thyroxin (FT4) or free triiodothyronine (FT3) may also displace thyroxin (T4) or triiodothyronine (T3) from thyroxin-binding globulin (TBG), resulting in an apparent TBG dependence of results of free hormone estimates. We used equilibrium dialysis and antibody binding to assess the displacement of ...

This paper presents a neural time-base generator TBG that can generate a family of neural control signals with a controllable finite duration and bell-shaped velocity profile. Then, a bio-mimetic trajectory generation method using the neural TBG model is explained. Using the proposed model, the generation ability of human-like trajectories is examined through comparisons between computer simula...