Taurine is a sulfur-containing amino acid-like endogenous compound found in substantial amounts in mammalian tissues. It exerts a diverse array of biological effects, including cardiovascular regulation, antioxidation, modulation of ion transport, membrane stabilization, osmoregulation, modulation of neurotransmission, bile acid conjugation, hypolipidemia, antiplatelet activity and modulation o...

Diabetic cataract is an ocular disease represented as blindness by lens opacification. Oxidative as well as osmotic stress caused by accumulation of polyols within the lens has been shown to be associated with glucose-induced cataractogenesis. Taurine has an antioxidant capacity and its level in diabetic cataractous lens is markedly decreased. Therefore, we investigated whether taurine is a par...

b a c k g r o u n d & aim: the aim of the current study was to investigate the advantages of bayesian method in comparison to traditional methods to detect best antioxidant in freezing of human male gametes. methods  &  materials:   semen  samples  were  obtained  from  40  men  whose  sperm  had  normal criteria. a part of each sample was separated without antioxidant  as fresh and the remaini...

Norwegian reindeer of Finnmark county live under harsh conditions on extensive feed sources. Thus the meat may have special qualities. M. longissimus lumborum from 30 animals was investigated with respect to carcass and meat quality and compositional/nutritional characteristics. Meat from calves had a higher myofibrillar fragmentation index and tenderness, and had lighter, redder and more yello...

There are several animal experiments showing that high doses of ionizing radiation lead to strongly enhanced leakage of taurine from damaged cells into the extracellular fluid, followed by enhanced urinary excretion. This radiation-induced taurine depletion can itself have various harmful effects (as will also be the case when taurine depletion is due to other causes, such as alcohol abuse or c...

BACKGROUND The complete blood count is one of the most common routine tests. This study aimed to evaluate possible effects of the antioxidant taurine on the complete blood count of whole blood stored at room temperature and at 4ºC over seven days. METHODS Venous blood samples of 25 healthy males were distributed into two sets of tubes with each set of four tubes containing 50 µL of solutions ...

In humans, taurine (2-aminoethanesulfonic acid) is mainly obtained from diet. Despite the fact that the health effects of taurine are largely unknown, taurine has become a popular supplement and ingredient in energy drinks in recent years. Evidence from mechanistic and animal studies has shown that the main biological actions of taurine include its ability to conjugate bile acids, regulate bloo...

Amodiaquine is an antimalarial drug used in the prophylaxis and treatment of this disease. However, hepatotoxicity as a life-threatening adverse effect is associated with its clinical use. We evaluated amodiaquine-induced toxicity in isolated rat hepatocytes as an in vitro model for studying drug-induced hepatotoxicity. This study attempts to investigate the protective effects of taurine and N-...

Acute lung injury (ALI), a serious respiratory distress has been associated with considerable human morbidity and mortality. Taurine, a physiological semi-essential amino acid has been shown to be tissue-protective in several models of oxidant-induced injury. Therefore, the current study was designed to explore protective effects of the taurine in ALI mice models. The possible tissue protective...