نتایج جستجو برای: targeted peptide
تعداد نتایج: 304789 فیلتر نتایج به سال:
milk proteins provide a natural source of bioactive peptides with potential health benefits and applications in the food industry. the release of these peptides from milk proteins is achieved either by hydrolysis using digestive proteases or by lactic acid bacteria fermentation. peptides, particularly those derived from milk proteins, can exert a wide range of nutritional, functional and biolog...
glaucoma is the second leading cause of irreversible blindness and a neurodegenerative disease with a complex pathogenesis. increasing evidence suggests that oxidative stress and mitochondrial dysfunction have crucial roles in most neurodegenerative diseases such as glaucoma. the conventional clinical treatment for glaucoma is lowering the intraocular pressure (iop). some patients have normal i...
The alpha-helical amphipathic peptide D-(KLAKLAK)2 is toxic to eukaryotic cells if internalized by a suitable targeting mechanism. We have targeted this peptide to malignant hemopoietic cells via conjugation to monoclonal antibodies, which recognize lineage-specific cell surface molecules. An anti-CD19/peptide conjugate efficiently killed 3/3 B lymphoid lines. However, an anti-CD33/peptide conj...
Breast cancer, with around 2 million new cases in 2019, is the second most common cancer worldwide and leading cause of death among females. The aim this work to prepare a targeting nanoparticle through conjugation LinTT1 peptide, specific molecule p32 protein overexpressed by breast associated cells, on liposomes’ surface. This approach increases cytotoxic effects doxorubicin (DOX) sorafenib (...
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