Clinical handoffs are tools aimed at bridging gaps that occur during transitions in care, whether across time (eg, shift changes) or across organisational boundaries (eg, the ward to the intensive care unit). They have long been viewed as potential threats to safety and are attracting increasing attention for several reasons. First, from a control theory point of view, handoffs are inherently h...

I HAS frequently beets suggested thatsulfhydryl comupounds may have an imuport-ant role imi cellular n etabo1ismn amid in cell growth and (livisiotu. Tints simlfhydryi (SH) comispoumids have I)een showis to stimumlate misitosis its a wide variety of cells amid tissues. Substances which oxidize SH comnpouticls (SI-I S-S) or coml)imie wit-h SH groimps to inactivate thetis have beets fouuid to inh...

One of the computational grand challenge problems is the development of methodology capable of sampling conformational equilibria in systems characterized by rough energy landscapes. If met, many important problems, most notably biomolecular structure prediction and the discovery of the polymorphism in organic molecular crystals could be significantly impacted. In this talk, I will discuss seve...