PURPOSE To determine whether uridine diphosphate-glucuronosyltransferase 1A1, UGT1A7, and UGT1A9 polymorphisms affect the pharmacokinetics (PK) of irinotecan and treatment outcome of Korean patients with advanced non-small-cell lung cancer (NSCLC). METHODS Eighty-one patients with advanced NSCLC were treated with irinotecan (80 mg/m2) on day 1 and 8 and cisplatin (60 mg/m2) on day 1 intraveno...

this study was designed to present and compare iranian hospitals` performance applying ratio analysis technique.this cross-sectional survey was conducted to present an instant image of 139 iranian hospitals` performance status applying ratio analysis as one of the non parametric technical efficiency assessment methods in 2008. data was collected using nine dimensional questionnaires supported b...

Type Ia supernovae (SNe) play a key role in the determination of the cosmological parameters because their absolute luminosities can directly be derived from measurements of their light curves. Despite several decades of observations and theoretical studies, the nature of SN Ia progenitors is still unknown, and this fact brings ambiguity into the interpretation of recent cosmological results. O...

OBJECTIVE Schmorl's nodes (SN) are common, but little is known of their relationship with degenerative change and back pain or genetic and environmental factors influencing their expression. We studied healthy female twin volunteers to determine the prevalence and clinical features associated with SN. METHODS Serial sagittal T1- and T2-weighted magnetic resonance images of the lower thoracic ...

Recent measurements of the cosmic ray (CR) antiproton flux have been shown to challenge existing CR propagation models. It was shown that the reacceleration models designed to match secondary to primary nuclei ratios (e.g., B/C) produce too few antiprotons. In the present paper we discuss one possibility to overcome these difficulties. Using the measured antiproton flux and B/C ratio to fix the...

The title tetra-nuclear Sn(IV) compound, [Sn(4)(C(7)H(6)Cl)(8)Cl(2)O(2)(OH)(2)], has site symmetry . Two O(2-) and two OH(-) anions bridge four Sn(IV) cations to form the tetra-nuclear compound. The two independent Sn(IV) cations assume SnO(3)C(2) and SnO(2)C(2)Cl distorted trigonal-bipyramidal coordination geometries. Intra-molecular O-H⋯Cl hydrogen bonding is present in the structure. One Cl ...

Tin doped In2S3 films were grown by the chemical spray pyrolysis (CSP) method using the pneumatic spray set-up and compressed air as a carrier gas. The spraying solution contained indium chloride (InCl3), thiourea [CS(NH2)2] and (SnCl4) at a molar ratio of S/In = 2.5. The deposition was carried out at 350 °C on glass substrates. The Sn doping level was changed with Sn/In = 0-8 % in solution. Th...

A series of bimetallic Sn-Pd catalysts were prepared by a template-free two step electrodeposition method. According to this method, Sn was electrodeposited firstly in potentiostatic or galvanostatic regime on Cu electrodes the form dendrites, then Pd galvanostatically second electrode with dendrites. The produced electrocatalysts compared an electrocatalyst obtained bare electrode. morphologic...

In this paper, three-dimensional elasto-plastic finite element analysis was performed on flexible pavements under vertical repeated traffic loads to evaluate their shakedown behavior. Six different pavements with different structural number (SN) were modeled and subjected to a wide range of cyclic vehicle loads. Shakedown limits were obtained considering both failure and serviceability restrain...

This is well known that the selectivity and sensitivity of tin dioxide (SnO2) thin film sensors for the detection of low concentration of volatile sulfides such as H2S in air can be improved by small amount of Ag additives. In this paper we present the results of comparative X-ray photoelectron spectroscopy (XPS), thermal desorption spectroscopy (TDS), and atomic force microscopy (AFM) studies ...