We generalize l ocal l exicographic SSOR preconditioning for the Sheikholeslami-Wohlert improved Wilson fermion action and the truncated perfect free fermion action. In our test implementation we achieve performance gains as known from SSOR preconditioning of the standard Wilson fermion action.

The production of heterologous selenoproteins in Escherichia coli necessitates the design of a secondary structure in the mRNA forming a selenocysteine insertion sequence (SECIS) element compatible with SelB, the elongation factor for selenocysteine insertion at a predefined UGA codon. SelB competes with release factor 2 (RF2) catalyzing translational termination at UGA. Stoichiometry between m...

Homologous recombination affects myriad aspects of genome evolution, from standing levels of nucleotide diversity to the efficacy of natural selection. Rates of crossing over show marked variability at all scales surveyed, including species-, population-, and individual-level differences. Even within genomes, crossovers are nonrandomly distributed in a wide diversity of taxa. Although intra- an...

Inducible expression systems in which T7 RNA polymerase transcribes coding sequences cloned under control of a T7lac promoter efficiently produce a wide variety of proteins in Escherichia coli. Investigation of factors that affect stability, growth, and induction of T7 expression strains in shaking vessels led to the recognition that sporadic, unintended induction of expression in complex media...

INTRODUCTION It has previously been reported that patients aged over 65 years account for 15% of Accident and Emergency (A&E) attendances. Despite this, there have been few studies looking at older people's use of A&E. This study describes the A&E attendance patterns of older people, defined as those aged 65 years and over, using data from an NHS region over a number of years. Their attendances...

The MUS-81, SLX-1, and XPF-1 structureselective endonucleases have been implicated in meiotic crossover (CO) formation in a variety of organisms, but their contributions to C. elegans CO formation have been unclear. In this issue of PLOS Genetics, Agostinho et al., Saito et al., and O’Neil et al. demonstrate that MUS-81 and XPF-1 function in two parallel pathways during the formation of meiotic...

Robyn Ott is the 2004-2005 Managing Editor for the Oklahoma Journal of Law and Technology. She wrote this eBrief while working under the direction of Professor Drew Kershen on the Project on Intellectual Property Rights in Living Matter. Below, Ms. Ott gives an overview of patentability requirements in India for plants, animals, and microorganisms. India is a signatory country to the Trade Rela...

OBJECTIVE The goal was to determine whether breakfast had effects on the cognitive performance and mood of high school students. METHODS A crossover trial was performed in boarding schools, involving 104 students between 13 and 20 years of age. The participants were randomly assigned to 2 equal-size groups on the morning of the first testing day. One half of the total sample received a standa...