Background: Anti-angiogenic therapy is a crucial step in cancer treatment. The discovery of new anti-angiogenic compounds from marine organisms has become an attractive concept in anti-cancer therapy. Because little data correlated to the pro- and anti-angiogenic efficacies of Ophiuroidea, which include brittle star, the current study was designed to explore the anti-angiogenic potential of bri...

let g be a (p, q) graph. let k be an integer with 2 ≤ k ≤ p and f from v (g) to the set {1, 2, . . . , k} be a map. for each edge uv, assign the label |f(u) − f(v)|. the function f is called a k-difference cordial labeling of g if |νf (i) − vf (j)| ≤ 1 and |ef (0) − ef (1)| ≤ 1 where vf (x) denotes the number of vertices labelled with x (x ∈ {1, 2 . . . , k}), ef (1) and ef (0) respectively den...

background: iron chelators are an important part of management of patients with thalassemia. it is prudent to compare efficacy of different iron chelators in treatment of iron overload in these patients who receive regular blood transfusion. we aimed to compare the efficacy and safety of available oral iron chelator; deferasirox (exjade®) with deferasirox (osveral®) in reducing iron overload in...

it is well know that any three impedances or admittances connected into each other in a star form can be easily transformed to a new three impedances or admittances connected into each other in a mesh form. in this paper a generalization of this fact is established and it is shown that in an n + 1 node network which is connected in a form it is always possible to eliminate the center node and o...

materials and methods samples were collected from six different farms and milk factories in iran, and were tested by beta-star and cylinder-plate methods. results among 992 raw milk samples, 236 positive samples, 9 suspected and 747 negative samples in respond to beta-star test and among 236 samples, which had positive responses to beta-star test, 28 positive, 0 suspected and 208 negative resul...

We have carried out a series of small scale collisional N-body calculations of single-mass star clusters to investigate the dependence of the lifetime of star clusters on their initial parameters. Our models move through an external galaxy potential with a logarithmic density profile and they are limited by a cut-off radius. In order to find scaling relations between the lifetime of star cluste...

Marine saponins are naturally glycosides compounds which possess important biomedical properties such as anti-cancer, antioxidant and anti-inflammatory. Nevertheless, no systematic studies on the anti-inflammatory potential of brittle star saponin and its underlying mechanisms have been reported. In this study, Ophiocoma erinaceus extracted saponin was investigated for its in vitro anti-inflamm...