• A comparison between ten methods for computing the T 2 distribution was performed. Various regularization techniques and penalty functions were tested. Our findings demonstrated need regularization. list of recommendations selecting optimal algorithms provided. The implemented packaged in a freely distributed toolbox. Multi-component relaxometry allows probing tissue microstructure by assessi...

Background Current approaches to evaluate peripheral arterial disease (PAD) overwhelmingly rely on quantification of stenosis severity or flow across stenosis at rest. Although exerciseinduced functional alterations in metabolism have been proposed, there is a need to integrate approaches that provide additional risk measures in PAD that can be translated into clinical practice [1]. Recently, q...

To further investigate the effect of dilute acid pretreatment (DAP) and steam explosion pretreatment (SE) on the change in cellulose accessibility, several techniques were applied including a Simons' stain (SS) technique along with several NMR methods (i.e., NMR cryoporometry, (1)H spin-lattice (T1) and (1)H spin-spin (T2) relaxometry, and diffusometry). These methods were utilized to probe bio...

OBJECTIVES The reproducibility of quantitative cerebral T2 relaxometry, diffusion tensor imaging, and H magnetic resonance (MR) spectroscopic imaging was assessed on a clinical 3.0 T MR system. MATERIALS AND METHODS Repeated measurements in 10 healthy volunteers were used to establish the reproducibility of quantitative measures derived from different quantitative MR techniques, namely the T2...

Mesial temporal sclerosis (MTS) is the most common known pathologic substrate of epilepsy. Accurate preoperative identification of unilateral MTS bymagnetic resonance (MR) imaging has had a tremendous impact on the clinical management of medically refractory seizures. It was well known in the pre-MR era that obtaining a temporal lobectomy specimen that contained MTS conferred a higher probabili...

INTRODUCTION Deep brain stimulation (DBS) nowadays is a well-established treatment of motor symptoms in Parkinson's disease. The subthalamic nucleus (STN) is a common target for DBS, because motor improvements have been shown to be superior to best medical therapy, if DBS electrodes have been appropriately positioned. DBS target identification can be assisted by MRI beyond structural imaging by...