background: iron chelators are an important part of management of patients with thalassemia. it is prudent to compare efficacy of different iron chelators in treatment of iron overload in these patients who receive regular blood transfusion. we aimed to compare the efficacy and safety of available oral iron chelator; deferasirox (exjade®) with deferasirox (osveral®) in reducing iron overload in...

We exhibit a theoretically founded algorithm T2 for agnostic PAC-learning of decision trees of at most 2 levels, whose computation time is almost linear in the size of the training set. We evaluate the performance of this learning algorithm T2 on 15 common “real-world” datasets, and show that for most of these datasets T2 provides simple decision trees with little or no loss in predictive power...

Wood length variability can affect operational yield and productivity in harvesting forest transport operations. Assertive lengths meet positive quality criteria for the product to cellulose factory delivered. Therefore, research is needed assess assertiveness measuring wood logs' length. Thus, objective was evaluate sensor accuracy at different positions harvester head. The following treatment...

We use an information theoretical framework to estimate the probability of the score of gapped alignments. With appropriate scaling, the score of a global (and with some adjustments also the score of a local) alignment of two sequences can be viewed as the difference in the number of bits needed to transmit the two sequences T1 and T2 under two different encoding schemes C1 and C2. C1 is an ide...

In this paper we build on previous work for estimation of the bivariate distribution of the time variables T1 and T2 when they are observable only on the condition that one of the time variables, say T1, is greater than (lefttruncation) or less than (right truncation) some observed time variable C1. In this paper, we introduce several results based on the In uence Curve (which we derive in this...

In this paper we build on previous work for estimation of the bivariate distribution of the time variables T1 and T2 when they are observable only on the condition that one of the time variables, say T1, is greater than (left-truncation) or less than (right truncation) some observed time variable C1. In this paper, we introduce several results based on the Influence Curve (which we derive in th...

PURPOSE To assess if 1.5T MRI can be used to study the transport to the liver, the intrahepatic distribution and engraftment of iron-oxide labelled hepatocytes in cyclophosphamide-treated and untreated mice. MATERIALS AND METHODS Hepatocytes were isolated from C57bl/6 mice and were labelled with 1.63 microm iron-oxide particles. Seventeen mice were pretreated with cyclophosphamide to disrupt ...

BACKGROUND AND PURPOSE Recent research has shown that a T2* image (either magnitude or phase) is not identical to the internal spatial distribution of a magnetic susceptibility (χ) source. In this paper, we examine the reasons behind these differences by looking into the insights of T2*-weighted magnetic resonance imaging (T2*MRI) and provide numerical characterizations of the source/image mism...

Background Demonstration of myocardial oedema following MI allows differentiation of acute and chronic MI, and assessment of the area at risk of infarction. T2-weighted dark blood TSE imaging for oedema is technically demanding and prone to artefacts. Our protocol for patients with acute MI include standard oedema imaging sequences and more recently T2 prepared single shot SSFP sequences, follo...