T helper 17 (T(H)17) is a novel subset of T helper cells that has recently been identified in the hepatocellular carcinoma (HCC) tumor environment. Its presence seems to be linked with HCC progression, possibly via facilitating angiogenesis. The origin of tumor-associated T(H)17 may be related to the gut, in which the differentiation of T cells, especially T(H)17 cells, is affected by microbiot...

interleukin (il)-17-producing t helper (th)-17 cells have recently been explained as a distinct population  of  cd4+  t  cells which play an important  role in immunity against infectious agents. establishment of persistent phenotype of th17 cells and recognition of lineage-deviating factors are of most attractive goals in modern researches in immunology. although  il-6  and  tgf-β  are  freque...

Background: Preeclampsia is a common pregnancy-specific disorder associated with significant maternal and fetal morbidity and mortality worldwide. It has been proposed that the imbalance between two CD4+ T cell subtypes, regulatory T cells (Treg) and T-helper 17 cells (Th17), is involved in the pathophysiology of preeclampsia. Objectives: To determine the serum levels of IL-17, IL-21, IL-23 and...

The aryl hydrocarbon receptor (AhR) has been shown to be required for optimal Thelper (Th) 17 cell activation. Th17 cells provide immunity against extracellular pathogens and are implicated in autoimmune diseases. Herein, the role of the AhR in cytokine production by Th17, and by the analogous population of T cytotoxic (Tc)17 cells, has been examined. Lymph node Tc (CD8(+)) and Th (CD4(+)) cell...

Citation: Baricza E, Marton N, Királyhidi P, Kovács OT, Kovácsné Székely I, Lajkó E, Kőhidai L, Rojkovich B, Érsek B, Buzás EI and Nagy G (2018) Distinct In Vitro T-Helper 17 Differentiation Capacity of Peripheral Naive T Cells in Rheumatoid and Psoriatic Arthritis. Front. Immunol. 9:606. doi: 10.3389/fimmu.2018.00606 Distinct In Vitro T-helper 17 Differentiation capacity of Peripheral naive T ...

background and objectives: infection with human immunodeficiency virus (hiv) results in dysregulation of the cytokine profile. a switch from a t helper 1 (th1) to a th2 cytokine has been proposed as an important factor in progression of hiv infection to aids. the aim of the present study was to assess the level of th1 and th2 cytokines in hiv infected individuals in order to identify the switch...