background: diagnosis and treatment of neuropsychiatric lupus is still a major challenge in clinical practice. we investigated the association between depression and anti-ribosomal p (anti-p) antibodies in a sample of iranian patients with systemic lupus erythematosus (sle). materials and methods: th is cross-sectional study was conducted on adult patients with sle referring to a referral out-p...

a 21 years old woman presented with a history of sle and skin lesions on the arms, trunk, and abdomen. the left gluteal region was ulcerated and painful and occasionally extruded a chalky white material. the patient referred from rheumatology department for osteomyelitis assessment. on physical examination the patient had hard, nontender lesions on the proximal arms, lower abdomen and lower bac...

objective: hla-g is a nonclassical major histocompatibility complex antigen and is expressed as seven isoforms, including four membrane bound (hla-g1 to –g4) and three soluble (hla-g5 to –g7) forms. the pattern of selective expression of hla-g transcripts in tissues shows the existence of a tight transcriptional control on the gene expression. it has been revealed that cytokines including inter...

background and objectives: this research study was conducted to determine the correlation between the clinicopathologic features and the outcome of membranous nephropathy. materials and methods: data were retrospectively reviewed from all patients with a diagnosis of membranous nephropathy. demographic, initial laboratory, and clinical findings were collected and the biopsy specimens were revie...

background systemic lupus erythematosus (sle) is an autoimmune connective-tissue disease involving multiple organs and systems. some evidence has demonstrated that disease activity could be associated with increased risk of organ damage. objectives the aim of this study was to determine the association between systemic lupus erythematosus disease activity index (sledai) scores and subclinical c...

introduction: systemic lupus erythematosus (sle) is an autoimmune disease affect nearly every organ system. pulmonary involvement, which is a common manifestation of sle, can remain undiagnosed if asymptomatic. this study aimed to evaluate the efficiency of spirometric findings in early detection of silent pulmonary involvement and examine its correlation with the six minute walk test in sle pa...

introduction systemic lupus erythematosus (sle) is a complex autoimmune and inflammatory disease. many studies show hla alleles can be associated with sle. the aim of this study was to determine the association of hla-drb1 alleles with juvenile- onset in iranian children. materials and methods at a case – control study, 31 children with systemic lupus erythematosus (case group) who referred to ...

this paper presents a 54-year-old female with lupus whom severe anaemia due to pure red cell aplasia (prca) was the first manifestation. there was seven years interval between prca onset and diagnosis of lupus. thymectomy due to thymoma had been carried out six years before but anaemia sustained. hypothyroidism and hypoparathyroidism were other associated diseases. severe anaemia and the need f...

The lupus anticoagulant was found in the plasma of 31 of 60 patients with systemic lupus erythematosus and other connective tissue disorders (mixed connective tissue disease, systemic vasculitis, polyarteritis nodosa, primary sicca syndrome, discoid lupus, Behcet's syndrome, and systemic sclerosis). Strong associations were found with biological false positive seroreaction for syphilis and thro...