an increase in c-reactive protein inflammatory indicator and lipid profile is accompanied with an increase in cardiovascular risks. however, the effect of resistance exercises on these cardiovascular risk factors in females is unknown.the aim of this study was to examine the effect of 12 weeks of circuit exercise on c-reactive protein and lipid profile in inactive women.for this purpose, 24 you...

Epigenetics is the study of heritable changes in gene expression without concomitant changes in DNA sequence. Due to its relevance in development, differentiation and human health, epigenetics has recently become an emerging area of science with regard to eukaryotic organisms and has shown enormous potential in synthetic biology. However, significant examples of epigenetic regulation in bacteri...

Synthetic circuits offer great promise for generating insights into nature's underlying design principles or forward engineering novel biotechnology applications. However, construction of these circuits is not straightforward. Synthetic circuits generally consist of components optimized to function in their natural context, not in the context of the synthetic circuit. Combining mathematical mod...

This brief proposes an on-line transparent test technique for detection of latent hard faults which develop in first input firstoutput buffers of routers during field operation of NoC. The technique involves repeating tests periodically to prevent accumulation of faults. A prototype implementation of the proposed test algorithm has been integrated into the router-channel interface and on-line t...

Phenotypic diversification of cells is crucial for developmental and regenerative processes in multicellular organisms. The diversification concept is described as the motion of marbles rolling down Waddington's landscape, in which the number of stable states changes as development proceeds. In contrast to this simple concept, the complexity of natural biomolecular processes prevents comprehens...

The emerging field of synthetic biology builds gene circuits for scientific, industrial and therapeutic needs. Adaptability of synthetic gene circuits across different organisms could enable a synthetic biology pipeline, where circuits are designed in silico, characterized in microbes and reimplemented in mammalian settings for practical usage. However, the processes affecting gene circuit adap...

We consider the problem of mapping a logical quantum circuit onto given hardware with limited 2-qubit connectivity. model this as an integer linear program, using network flow formulation binary variables that includes initial allocation qubits and their routing. several cost functions: approximation fidelity circuit, its total depth, measure cross-talk, all which can be incorporated in model. ...