نتایج جستجو برای: synergistic mechanism

تعداد نتایج: 599368  

Journal: :Chemical communications 2012
Guangxi Huang Guanxin Zhang Deqing Zhang

The fluorescence of tetra(4-pyridylphenyl)ethylene (1) can be switched on significantly by the synergistic interactions of Hg(2+) and HSO(4)(-) based on a new aggregation mechanism for tetraphenylethylene molecules.

Journal: :Molecular cancer research : MCR 2007
Sucharita J Mistry Alexander Bank George F Atweh

Stathmin is one of the key regulators of the microtubule cytoskeleton and the mitotic spindle in eukaryotic cells. It is expressed at high levels in a wide variety of human cancers and may provide an attractive target for cancer therapy. We had previously shown that stathmin inhibition results in the abrogation of the malignant phenotype. The microtubule-interfering drug, taxol, has both antitu...

Jiang-nan Yu Li Wang, Min Peng, Shan-shan Tong Xi-ming Xu Xia Cao Yuan Zhu,

Pluronic/bile salt/phospholipid mixed micelles (Pluronic/BS/PS-MM) drug carrier system for solubilization hydrophobic drugs was developed. A typical hydrophobic compound, pyrene, was selected as a representative hydrophobic compound to model the hydrophobic drugs. Five Pluronics, F68, F88, F98, F108, and F127 with different PPO chain length were studied. CMC data and solubilization capacities w...

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