نتایج جستجو برای: syndrome of inappropriate secretion of adh
تعداد نتایج: 21262099 فیلتر نتایج به سال:
Syndrome of inappropriate antidiuretic hormone secretion (SIADH) not only induces uncharacteristic clinical symptoms but also increases morbidity and mortality [1, 2]. The recent introduction of vaptans acting as V2-receptor antagonists considerably improved the unconvincing results of conventional treatment consisting of fluid restriction potentially combined with sodium supplementation and/or...
Academic integrity encompasses a number of values including honesty, trust, respect, fairness, and responsibility [1] and ideals that should be upheld by all educational stakeholders. ‘‘Academic integrity involves ensuring that in research, and in teaching and learning, both staff and students act in an honest way. They need to acknowledge the intellectual contributions of others, be open and a...
Studies have shown that allowing people to answer questionnaires completely anonymously yields more reports of socially inappropriate attitudes, beliefs, and behaviors, and researchers have often assumed that this is evidence of increased honesty. But such evidence does not demonstrate that reports gathered under completely anonymous conditions are more accurate. Although complete anonymity may...
ecognition of and response to environmental challenge are expressed in part by the availability and efficacy of circulating hormones for R the modulation of intermediary metabolism in target cells. One example of such adaptive capability that changes during aging is the impact of dietary glucose on its insulin-sensitive metabolism by liver and peripheral tissues. This paper provides a critical ...
The hypertonic saline test is a useful technique for distinguishing partial diabetes insipidus from psychogenic polydipsia, and for the diagnosis of complex disorders of osmoreceptor and posterior pituitary function. However, there is little information concerning its use in childhood. The experience of using this test in five children (11 months to 18 years) who presented diagnostic problems i...
Metastases to the pituitary gland are rare; cancers that most commonly metastasize to the pituitary are breast and lung cancers. No specific computed tomography or magnetic resonance imaging features reliably distinguish primary pituitary masses from metastases. A combination of a detailed clinical assessment together with specialist endocrine and neuroradiology support is essential to make the...
Olfactory neuroblastoma (ONB) is a rare malignant neoplasm of sinonasal tract, derived from olfactory epithelium. Unilateral nasal obstruction, epistaxis, sinusitis, and headaches are common symptoms. Olfactory neuroblastoma shows neuroendocrine differentiation and similarly to other neuroendocrine tumors can produce several types of peptic substances and hormones. Excess production of these su...
The syndrome of inappropriate antidiuretic hormone secretion (SIADH) has been recognized to occur following treatment with vincristine. None of the reports have provided information regarding its potential for recurrence on further challenge with vincristine (VCR), an agent generally required for repeated use in patients with malignancies. Symptomatic hyponatremia and SIADH that occurred 8 days...
The nephrogenic syndrome of inappropriate antidiuresis (NSIAD) is a rare, recently recognized disorder in water balance affecting not only infants but also adults. A new molecular mechanism responsible for NSIAD has recently been identified: a gain of function of the arginine vasopressin (AVP) receptor type 2 (V2R), causing the constitutive activation of the receptor. Clinical presentation and ...
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