BACKGROUND The purpose of this study was to determine the appropriate recommendations for weaning off cardiopulmonary support (CPS) in children with fulminant myocarditis. METHODS AND RESULTS Four consecutive patients diagnosed with fulminant myocarditis who were treated with CPS were enrolled (mean age: 9 years). The relationships between timing of weaning from CPS and various factors, inclu...

OBJECTIVES Although fluid resuscitation guided by central venous oxygen saturation (SvcO2) is currently considered the gold standard in sepsis therapy, few studies have described hemodynamic and perfusion parameters during this procedure. This study aims to describe these parameters during septic shock without resuscitation and after 12 hours of goal-directed resuscitation. METHODS Thirteen a...

Heart rate telemetry is frequently used to estimate daily activity in children and to validate other methods. This study compared the accuracy of heart rate monitoring, pedometry, triaxial accelerometry, and uniaxial accelerometry for estimating oxygen consumption during typical children's activities. Thirty Welsh children (mean age 9.2 +/- 0.8 yr) walked (4 and 6 km/h) and ran (8 and 10 km/h) ...

Purpose. To evaluate the oxygen saturation in retinal blood vessels in patients after closed-globe blunt ocular trauma. Design. Retrospective observational case series. Methods. Retinal oximetry was performed in both eyes of 29 patients with unilateral closed-globe blunt ocular trauma. Arterial oxygen saturation (SaO2), venous oxygen saturation (SvO2), arteriovenous difference in oxygen saturat...

OBJECTIVE To determine, even during postoperative period, the confiability of the cardiac index correlate with the data data given by a central atrial venous blood gasometry in patients who underwent cardiac surgery. METHODS From the sample of arterial and venous blood of right atrium gathered in postoperative of cardiac surgery, it was determinated the hemoglobin concentration and the gasome...

The frequency-domain multiple-distance (FDMD) method is capable of measuring the absolute absorption and reduced scattering coefficients of optically turbid media. Absolute measurement of absorption at two near-infrared (NIR) wavelengths makes possible the quantitation of tissue haemoglobin concentration and tissue haemoglobin oxygen-saturation (StO2). However, errors are introduced by the unce...

BACKGROUND To investigate possible effects of high thoracic epidural anesthesia (HTEA) on mixed venous oxygen saturation (SvO2) in coronary artery bypass grafting surgery (CABGS) MATERIAL AND METHODS: Sixty-four patients scheduled for CABGS were randomly assigned to either test (HTEA) or control group. Standard balanced general anesthesia was applied in both groups. Mean arterial blood pressure...

saturation (ScvO2) and mixed venous saturation (SvO2) in 53 patients with severe sepsis [1]. For several reasons, however, we feel the authors’ broadly stated conclusion that ‘a positive (ScvO2 SvO2) value is not associated with improved outcome’ is unwarranted. First, in Figure 3 of their paper, graphing the number of measurements rather than the number of subjects is counterintuitive; your re...

Mixed (SvO2) or central (ScvO2) venous oxygen saturation is frequently used to evaluate the adequacy of global tissue oxygenation in critically ill patients. The aim of this review is to discuss the literature regarding S(c)vO2 measurement and S(c)vO2 directed therapy. Both reductions in oxygen delivery and increases in oxygen consumption without subsequent adequate rise in cardiac output can r...

BACKGROUND Both age and smoking promote endothelial dysfunction and impair vascular reactivity. Here, we tested this hypothesis by quantifying new cardiovascular magnetic resonance (CMR)-based biomarkers in smokers and nonsmokers. METHODS Study population: young non-smokers (YNS: N = 45, mean age = 30.2 ± 0.7 years), young smokers (YS: N = 39 mean age 32.1 ± 0.7 years), older non-smokers (ONS...