نتایج جستجو برای: suppressive function
تعداد نتایج: 1223809 فیلتر نتایج به سال:
Nematode-suppressive soils are characterized by the ability of soil microbial communities to reduce populations plant-parasitic nematodes (PPN) either directly or inducing systemic resistance in plants. Various microorganisms have been recognized as antagonists PPN suppressive using culture-dependent and culture-independent methods. However, associations that form with nematode-conducive poorly...
Regulatory T (T(reg)) cells control immune activation and maintain tolerance. How T(regs) mediate their suppressive function is unclear. Here we identified a cell surface molecule, called GARP, (or LRRC32), which within T cells is specifically expressed in T(regs) activated through the T cell receptor (TCR). Ectopic expression of GARP in human naïve T (T(N)) cells inhibited their proliferation ...
Regulatory T cells (Tregs) are a subset of CD4(+) T cells that maintain immune tolerance in part by their ability to inhibit the proliferation of conventional CD4(+) T cells (Tconvs). The role of the TCR and the downstream signaling pathways required for this suppressive function of Tregs are not fully understood. To yield insight into how TCR-mediated signals influence Treg suppressive functio...
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