AIMS To compare the efficacy of and tolerance to oral fluconazole and intraconazole in preventing fungal infection in neutropenic patients with haematological malignancies. PATIENTS 213 consecutive, afebrile adult patients treated with or without autologous stem cell transplantation for haematological malignancies. METHODS A randomised, double blind, single centre study. Patients were rando...

abstract: background: a new type of drug delivery system known as mucoadhesive film has been developed for oral thrush treatment. due to comfortable use of this drug delivery system, this would be encouragingly utilized, especially in babies and patient under chemotherapy. nystatin mucoadhesive film (nmf) is a polymeric film which is adhered to front upper gum and back to the upper lip and rele...

OBJECTIVE To determine the prevalence of superficial mycoses among psychiatric patients. DESIGN Randomised Prospective study SETTING Mathari Mental Hospital, and Jomo Kenyatta University of Agriculture and Technology, Nairobi Kenya. RESULTS A study was conducted on prevalence of superficial fungal infections among psychiatric patients in Mathari Hospital, Nairobi, Kenya during the period ...

C. albicans is one of the most common fungal pathogen of humans, causing local and superficial mucosal infections in immunocompromised individuals. Given that the key structure mediating host-C. albicans interactions is the fungal cell wall, we aimed to identify features of the cell wall inducing epithelial responses and be associated with fungal pathogenesis. We demonstrate here the importance...

Geotrichosis is an uncommon fungal infection. Geotrichum capitatum is commonly acknowledged as an opportunistic fungal pathogen that causes systemic geotrichosis in immunocompromised patients, especially patients with acute leukemia and severe neutropenia. Here, we report a case of oral geotrichosis caused by G. capitatum in an old patient with no hematological malignancies. Fungal cells were d...

Yeasts cause only 5-10% of onychomycosis; the most common yeast is Candida albicans, and rarely Trichosporon spp. is found. Recently, it has become an important cause of fungemia with a high mortality rate in immunocompromised patients. Superficial infections caused by Trichosporon spp., including piedra and onychomycosis, occur in immunocompetent patients. Herein, we report a case of a fungal ...

BACKGROUND Dermatophyte infections are a common cause of superficial fungal infection in different geographical locations of the world. Usually, it involves superficial invasion of keratinized tissue, eg, skin, nails, and hair, but in immunosuppressed individuals, it may cause atypical, extensive and deep lesions, which may pose serious diagnostic and therapeutic challenges. AIM To find out t...

Pityriasis versicolor is a common superficial fungal infection of the skin which is caused by various species of yeast of the genus Malassezia and is clinically characterized by scaly hypo pigmented or hyper pigmented macules usually involving the upper trunk, upper arms, neck and abdomen [1]. Lesions of pityriasis versicolor confined to face has rarely been reported. In this article the author...

Pityriasis versicolor is a superficial fungal infection of the skin caused by yeast of the genus Malassezia. It is characterized by hypopigmented or hyperpigmented macules and patches usually involving the trunk [1]. The variants of pityriasis versicolor include hypochromic, hyperchromic, combination of hypo-hyperchromic, erythematous, circinate, atrophic and acral [2-4]. However, the follicula...