Interactions of nerve G-agents (sarin and soman) and their simulants DMMP (dimethyl methylphosphonate) and DIFP (diisopropyl fluorophosphate) with water and components of polyelectrolyte membranes are studied using ab initio calculations in conjunction with thermodynamic modeling using the conductor-like screening model for real solvents (COSMO-RS). To test reliability of COSMO-RS calculations,...

We introduce the use of block copolymer membranes for an emerging application, "drug capture". The polymer is incorporated in a new class of biomedical devices, referred to as ChemoFilter, which is an image-guided temporarily deployable endovascular device designed to increase the efficacy of chemotherapy-based cancer treatment. We show that block copolymer membranes consisting of functional su...

The applicability of time-temperature superposition of dynamic mechanical data for miscible polymer blends that exhibit strong intermolecular interactions was investigated. Blends of the lithium salt of lightly sulfonated polystyrene ionomers (Li-SPS), 9-12mol% sulfonation, and N-methylated nylon-2,lO (mPA) were miscible over the composition range studied, 30-70 wt% ionomer. Time-temperature su...

An accurate and precise mechanized ion-exchange chromatographic method for the estimation of polyamines in biological fluids is described. The method includes the recent improvements developed for ion-exchange analysis of polyamines: the use of sulfonated polystyrene cation-exchange resin with a bead diameter of less than 10 micrometers and a continuous fluorescent detection with o-phthalaldehy...

The present study has been undertaken to obtain information on the amino acids and related compounds of animal tissues by the chromatographic analysis of protein-free extracts on columns of sulfonated polystyrene resins (2). The nature and quantity of bound forms of amino acids have been investigated by analysis of the extracts before and after acid hydrolysis. The tissues of the cat were chose...

line tending to appear as a shoulder on the aspartic acid peak. Resolution could be improved, but at the expense of analysis time. To overcome these problems found with the ninhydrin method, we decided to adopt the column conditions of Callahan et al. (4), but to use a different chromogen (6, 7). The column eluate was oxidized with chloramine-T to give a pyrrole that condensed with Ehrlich’s al...

Functionalized mica sheets and polystyrene films exposing ionisable groups have been used as heterogeneous nucleating surfaces for model proteins. Surfaces with different densities of amino or sulfonated groups have been prepared. Crystallization trials were carried out using the hanging-drop vapour-diffusion method. The results show that using these surfaces the starting protein concentration ...

Solid-state NMR was used to establish the specific intermolecular interactions responsible for the miscibility of blends of nylon 6 (PA6) and the zinc salt of lightly sulfonated polystyrene (Zn-SPS) and to characterize the scale of molecular mixing. l 3 C CPIMAS spectroscopy identified the interpolymer interaction as a complex between the Zn2+ cation of the ionomer and the amide nitrogen. Measu...

Synthesis and characterization of the novel sulfonated BAPPO monomer and its use in the synthesis of a new phosphine oxide-based sulfonated polyimide are described. BTDA, 6FDA, and DDS were used as monomers in the polyimide synthesis. Sulfonated polyimide membranes were obtained by a solution thermal imidization method. The thermal behavior of the polymers was investigated by DSC and TGA. The m...