We have synthesized a pillar[6]arene in high yield and a co-pillar[6]arene using chlorocyclohexane as a solvent.

This paper reviews the data sources and methods used to estimate the number of people on, and coverage of, antiretroviral therapy (ART) programmes in low- and middle-income countries and to monitor the progress towards the "3 by 5" target set by WHO and UNAIDS. We include a review of the data sources used to estimate the coverage of ART programmes as well as the efforts made to avoid double cou...

Kytococcus schroeteri, a saprophyte of the human skin, may cause serious infections in the immunocompromised host. Here, we describe a case of pneumonia and bacteremia due to Kytococcus schroeteri in an immunocompromised patient, successfully treated with linezolid and trimethoprim-sulfamethoxazole.

I Alfa Institute of Gastroenterology, University Hospital, Federal University of Minas Gerais Belo Horizonte/MG, Brazil. II School of Medicine, Department of Internal Medicine Belo Horizonte/ MG, Brazil. III Department of Pathology and Legal Medicine, School of Medicine, Federal University of Minas Gerais Belo Horizonte/MG, Brazil. Email: [email protected] Tel.: 55 31 3409.9247 / 3409.92...

16 Thirty-three Salmonella Typhi blood isolates from Lima, Peru (2008-2012), were fully 17 susceptible to trimethoprim-sulfamethoxazole, chloramphenicol, ceftriaxone, and 18 tetracycline; 8/33 (24.2%) showed intermediate susceptibility to ciprofloxacin carrying 19 mutations in the quinolone resistance-determining region of the gyrA gene (Ser83-Phe and 20 Asp87-Asn); and in the gyrB gene (Ser464...

Two sources of rats free of latent Pneumocystis carinii are described. First, rats from a virus-free colony failed to develop infection after 8 weeks of immune suppression unless they were housed with previously infected rats. Second, pregnant rats (non-virus free) received trimethoprim-sulfamethoxazole from day 10 of gestation until the pups were weaned. Pups raised in filter-topped cages and ...

In contrast to prior experience in northeastern Brazil, three of four Shigella flexneri strains recently isolated from patients with acute inflammatory diarrhea in this setting were found to be resistant to sulfamethoxazole-trimethoprim. The resistant strains contained large, different plasmids, two of which were transferred with sulfamethoxazole-trimethoprim resistance to Escherichia coli K-12...

Four chronic typhoid carriers from the Aberdeen typhoid outbreak of 1964 were treated with trimethoprim-sulphamethoxazole. The male carrier remained clear of infection following treatment but the three female carriers, all with gall bladder abnormalities, remained excretors. A convalescent typhoid excretor also remained clear of infection after treatment as well as two other salmonella carriers...

BACKGROUND To support antibiotic prescribing for both hospital and community-based health professionals working in remote North Western Australia, a multidisciplinary Antimicrobial Stewardship (AMS) Committee was established in 2013. This Committee is usually focused on hospital-based prescribing. A troubling increase in sulfamethoxazole/trimethoprim resistance in Staphylococcus aureus antibiog...