this study aimed to investigate the effects of different doses of sulfadiazine on embryonic chicken pectoral muscles. in total, 100 fertile eggs were obtained and divided into five groups of control (no injection) and sulfadiazine injection at doses of 2, 10, 30, and 70 mg/kg. after hatching, pectoral muscle tissues were harvested from the newly hatched chickens for histopathological examinatio...

aloe vera is a tropical plant belonging to the liliaceae family. it has beneficialeffects in variety of diseases. the aim of this study was to formulate a topical cream from a. vera with wound burn healing effect and to perform its clinical trial. a total of 30 patients (20 males and 10 females in the age range of 20-50 years) with second degree burn wounds on their both hands were selected for...

background numerous studies were carried out to develop more sophisticated dressings to expedite healing processes and diminish the bacterial burden in burn wounds. this study assessed the healing effect of nettle extract on second degree burns wound in rats in comparison with silver sulfadiazine and vaseline. methods forty rats were randomly assigned to four equal groups. a deep second-degree ...

Current therapy for toxoplasmosis with a synergistic combination of pyrimethamine plus sulfadiazine or pyrimethamine plus clindamycin is not always efficacious and is frequently discontinued due to intolerable toxic effects in immunocompromised individuals, particularly those with AIDS. Trovafloxacin, a new fluoroquinolone with potent activity against Toxoplasma gondii, was examined for potenti...

Studies by Feinstone, Williams, Wolff, Huntington, and Crossley4 on the toxicity, absorption, and chemotherapeutic activity of this compound in mice, dogs, and monkeys indicate that it exhibits less acute and chronic toxicity than either sulfapyridine or sulfathiazole. In addition, these investigators found sulfadiazine to be readily absorbed, eliminated comparatively slowly, and acetylated to ...

Background and aim: Shortening of the duration of wound healing is an attractive subject for investigators in recent years. In this study, the effects of topical phenytoin, silver sulfadiazine, estrogen and their combination on wound healing were evaluated.Materials and Methods: This experimental study was accomplised on 30 male albino rats, which had an approximate wei...

Background: Major omphalocele is defined as an abdominal defect greater than 5 cm with the presence of liver and most parts bowel in sac. The management remains challenging for pediatricians surgeons remarkably high mortality. Reports about topical agents/dressing used escharotic therapy, such silver sulfadiazine, povidone-iodine, antibiotics, or honey, have been published different results. Co...

A liquid chromatographic (LC) method for determining 14 sulfonamide (SA) (sulfanilamide, sulfadiazine (SDZ), sulfathiazole, sulfapyridine, sulfamerazine (SMR), sulfamethazine (SMZ), sulfamethizole, sulfamethoxypyridazine, sulfachloropyridazine (SCP), sulfamonomethoxine, sulfadoxine, sulfamethoxazole, sulfadimethoxine (SDM), and sulfaquinoxaline (SQX)) residues in edible catfish, shrimp and salm...