An enzyme's substrate specificity is one of its most important characteristics. The quantitative comparison of broad-specificity enzymes requires the selection of a homogenous set of substrates for experimental testing, determination of substrate-specificity data and analysis using multivariate statistics. We describe a systematic analysis of the substrate specificities of nine wild-type and fo...

Paramjit S. Bansal, Allan M. Torres, Ben Crossett, Karen K. Y. Wong, Jennifer M. S. Koh, Dominic P. Geraghty, Jamie I. Vandenberg , and Philip W. Kuchel From the School of Molecular and Microbial Biosciences, University of Sydney, New South Wales 2006, Nanoscale Organisation and Dynamics Group, College of Health and Science, University of Western Sydney, Penrith South DC, New South Wales 1797, ...

1 To whom correspondence should be addressed: Institut de Biotecnologia i de Biomedicina & Departament de Bioquimica, Universitat Autonoma de Barcelona, IBB-Campus de la UAB, Bellaterra (Barcelona), 08193, Spain.Tel.: 34-935811231; Fax: 34-935812011; E-mail: [email protected] 2 To whom correspondence should be addressed: Dept. of Molecular Pharmacology, Albert Einstein College of Medicine, 1...

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