A novel synthetic methodology has been developed for the synthesis of diethyl 5-alkyl/aryl/heteroaryl substituted 3,4-dihydro-2H-pyrrole-4,4-dicarboxylates (also called 2-substituted pyrroline-4,5-dihydro-3,3-dicarboxylic acid diethyl esters) by iodide ion induced ring expansion of 2-[(aziridin-1-yl)-1-alkyl/aryl/heteroaryl-methylene]malonic acid diethyl esters in very good to excellent yields ...

1- and 1,5-Aminoalkylamine substituted anthraquinones (AAQs, 1C3 1,5C3) were peptide coupled to 1-, 2-, 3-pyrrole lexitropsins generate compounds that incorporated both DNA minor groove intercalating moieties. The corresponding platinum(II) amidine complexes synthesized through a synthetically facile amine-to-platinum mediated nitrile ‘Click’ reaction. precursors as well the biologically evalua...

Herein, we report on the mechanochemical reaction of pyrrole and substituted benzaldehyde precursors to produce freebase corroles demonstrate one-pot synthesis 5,10,15-Tris(4-t-butylphenyl)corrole (H3t-buPhC), in which both, condensation oxidation reactions steps, took place ball mill. Moreover, could achieve copper with decent overall yields 10–12%. With approach shift EcoScale obtained from c...

The substituted pyrrole monomer, N–(2–cyanoethyl)pyrrole, was electropolymerised in a 70% water and 30% ethanol solution with ClO4– H2PO4– as the dopant species to give nanowires at short electropolymerisation times microwires longer deposition periods. On adding toluene solution, hollow microtubes were formed. This attributed adsorption of droplets electrode surface which served separate dopan...

Structural, electronic and photovoltaic properties of pyrrole-furan copolymer incorporated with several electron-donating groups (EDGs) electron-withdrawing (EWGs) were investigated using density functional theory (DFT) time-dependent (TD-DFT). The intramolecular hydrogen bonding between the N…H site pyrrole O furan enhances a coplanar structure derivatives. substituted -NO2 shows significantly...

The title compounds, rac-(1'R,2R)-tert-butyl 2-(1'-hydroxyethyl)-3-(2-nitrophenyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, C(17)H(20)N(2)O(6), (I), rac-(1'S,2R)-tert-butyl 2-[1'-hydroxy-3'-(methoxycarbonyl)propyl]-3-(2-nitrophenyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, C(20)H(24)N(2)O(8), (II), and rac-(1'S,2R)-tert-butyl 2-(4'-bromo-1'-hydroxybutyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-car...

Various aryl and alkyl substituted optically pure propargyl alcohols were obtained with excellent ee (up to >99%) and isolated yields (up to 87%) by deracemization using whole cells of Candida parapsilosis ATCC 7330. The whole cells show substrate specificity towards alkyl substituted propargyl alcohols and a switch in the enantioselectivity has been observed from 'R' to 'S' upon increasing the...