We describe a patient with Noonan syndrome who presented with Human Leukocyte Antigen B27-associated recurrent acute anterior uveitis and manifestations of congenital fibrosis of the extraocular muscles, which has not been reported before.

purpose: to analyze the clinical patterns and etiologies of uveitis in isfahan. methods: the records of 2016 patients with uveitis who had been referred to the feiz tertiary eye care center, isfahan, between 1999 and 2013 were classified and analyzed with respect to demographic, clinical, anatomical, and etiological characteristics. results: at the onset of uveitis, the mean patient age was 33....

BACKGROUND The aim of this study was to assess the clinical course and distinctive features of different white dot syndromes (WDS) in patients attending the Ophthalmology Department, Medical University of Warsaw in the years 1995-2015. MATERIAL AND METHODS Sixty-two (62) patients (43 females and 19 males), aged 18 to 77 years, referred with a WDS were included in this prospective study, with ob...

Background: Idiopathic anterior uveitis is an anterior segment inflammation in which a detailed medical history, general and ocular physical examination is not associated with any defined clinical syndrome. Alterations in immune system parameters have been reported in patients with idiopathic posterior uveitis; however no data on the role of immune system in idiopathic anterior uveitis has yet ...

conclusions inter-rater accuracy could be improved at middle grades using renal ultrasonography (usg), which could promote communication between different specialists. results the intraclass correlation coefficient (icc) values ranging from 0.86 to 0.89 reflected good reliability. the lowest agreement was associated with middle grades (iii and iv). a marked difference in sensitivity was observe...

In the absence of replication of wells, empirical criteria for enzyme-linked immunospot (ELISpot) positivity use fixed differences or ratios between spot forming units (SFU) counts between test and control. We propose an alternative approach which first identifies the optimally variance-stabilizing transformation of the SFU counts, based on the Bland-Altman plot of the test and control wells. T...

OBJECTIVES The aim of the present study is to investigate the demographics, aetiologies, complications, treatments and visual outcomes in paediatric uveitis patients in the French-speaking part of Switzerland. METHODS Chart review of all patients diagnosed with uveitis before the age of 16 years, presenting to two tertiary referral centres (uveitis and paediatric rheumatology clinics) in Laus...

BACKGROUND At present, there is no standard of treatment using systemic high-dose corticosteroids in cases of pregnant women with Vogt-Koyanagi-Harada (VKH) disease. Although high-dose systemic corticosteroid treatment is often used for VKH disease during pregnancy, it also poses a risk to the fetus. FINDINGS A 29-year-old woman in the 34th week of pregnancy experienced bilateral metamorphops...