Subgingival calculus has been recognized as a major cause of periodontitis, which is one of the main chronic infectious diseases of oral cavities and a principal cause of tooth loss in humans. Bacteria deposited in subgingival calculus or plaque cause gingival inflammation, function deterioration, and then periodontitis. However, subgingival calculus within the periodontal pocket is a complicat...

Background and Aim: This study aimed to assess the antibody titer against Porphyromonas gingivalis (P. gingivalis) in rats with experimentally induced periodontitis. Materials and Methods: Thirty-three Surrey rats were randomly divided into three groups (n=11). Group 1 was vaccinated with formalin-killed whole cell (FKWC) P. gingivalis with incomplete Freund's adjuvant as vaccine carrier and o...

BACKGROUND AND OBJECTIVE Aggressive periodontitis (AgP) is prevalent and shows a rapid course in African individuals. Although a strong focus has been placed on Aggregatibacter actinomycetemcomitans, new methods support the existence of a complex subgingival microflora in AgP. The purpose of the present study was to map the subgingival microbiota as well as explore the presence of A. actinomyce...

Antimicrobial therapeutic strategies widely referred to as the Keyes Technique were directed at suppression of the periodontopathic microflora of 7 juvenile periodontitis patients who were treated and followed for at least 22 months. Following collection of baseline clinical and microbiological parameters, the patients received meticulous scaling and root planing of all teeth with concomitant i...

BACKGROUND, AIMS The purpose of the present study was to compare and relate the microbial composition of supra and subgingival plaque in 23 adult periodontitis subjects (mean age 51 +/- 14 years). METHODS A total of 1,170 samples of supra and subgingival plaque were collected from the mesial aspect of every tooth (up to 28 supra and 28 subgingival samples) from each subject and evaluated for ...

OBJECTIVE This study is a proof of concept to determine the efficacy of a custom-fabricated tray in placing antimicrobial and debriding agents in the periodontal pockets of persons with active gingival infections. Localized subgingival delivery of antimicrobial and antibiotic agents is routinely employed as adjunctive therapy for the treatment and management ofperiopathogens associated with per...

The purpose of this study was to identify and compare the presence of HCMV and EBV-1 in subgingival plaque, unstimulated saliva and peripheral blood of patients with chronic periodontitis. Forty patients diagnosed with chronic periodontitis (mean age, 41.7 years) were recruited. Unstimulated saliva, subgingival plaque and peripheral blood were collected from each patient and the DNA of each sam...

BACKGROUND Inflammatory periodontal diseases are found in many dentate individuals, but therapists and researchers who assess disease activity have had to rely on external clinical signs and symptoms to ascertain the health of the subgingival periodontal tissues. However, by using an endoscope in the subgingival environment, the therapist can see the relationship of subgingival tooth-borne accr...

PURPOSE This study was to observe the clinical effects of hyperbaric oxygen therapy combined with supragingival and subgingival scaling therapy on periodontitis. METHODS The patients with periodontitis were divided randomly into 3 groups, the supragingival and subgingival scaling therapy group, the hyperbaric oxygen therapy group, the hyperbaric oxygen combined with supragingival and subgingi...