Abstract Background Laminitis is a common and serve disease which caused by inflammation pathological changes of the laminar junction. However, pathologic mechanism remains unclear. In this study we aimed to investigate gut microbiota metabolomics in oligofructose-induced laminitis horses. Results Animals submitted treatment with oligofructose had lower fecal pH but higher lactic acid, histamin...

Lameness in dairy cows includes many disease conditions, and a systematic approach is required to diagnose the predominant causes and identify the important risk factors. Lameness prevalence can be quantified using locomotion scoring systems. Entire herds can be scored quite easily as they walk access lanes. If lameness prevalence exceeds 15% of the herd, it is important to differentiate the ca...

Background: Laminitis is a common but critical disease that causes severe pain and disability in horses. The etiology and pathogenesis of laminitis remain inconclusive and a multimodal therapeutic approach is generally indicated. Acupuncture has been used as a treatment option; however, the required number of treatments is still controversial due to the lack of objective scient...

Laminitis is one of the most common diseases in horses. It is not only painful for the animal, but also has a significant financial impact on the equine industry. This multifactorial disease affects the connective tissue of the hoof. However, the pathogenesis of laminitis is still not fully understood. Endotoxins, also known as lipopolysaccharides (LPS), and bacterial exotoxins seem to play an ...

In the past, many cases of laminitis have been of mysterious origin. Recent investigations in veterinary medicine, coupled with the availability of new techniques for analyzing hydrolyzable carbohydrates in forage may provide evidence to solve some of these mysteries. Fructan has been shown to be capable of inducing laminitis in clinical studies. Insulin resistance, a primary feature of Equine ...

One of the most important hoof diseases is laminitis. Yet, the pathology of laminitis is not fully understood. Different bacterial toxins, e.g. endotoxins or exotoxins, seem to play an important role. Additionally, ingestion of mycotoxins, toxic secondary metabolites of fungi, might contribute to the onset of laminitis. In this respect, fumonsins are of special interest since horses are regarde...