In an attempt to dissect the mechanism of Strychnos nuxvomica, a commonly used Chinese folk medicine in the therapy of liver cancer, the cytotoxic effects of four alkaloids in Strychnos nux-vomica, brucine, brucine N-oxide, strychnine, and isostrychnine, on human hepatoma cells (HepG2) were screened by 3-(4,5dimethylthiazol-2-yl)-2,5-diphenyl-tetrasolium bromide (MTT) assay. Brucine, among the ...

Vishamusthi (Strychnos nux-vomica Linn.), a medicinal plant described as Upavisha (semi-poisonous) group of Ayurvedic Pharmacopoeia India. has widely been used and being practiced in several illness namely nervous debility, paralysis, weakness limbs, sexual weakness, dyspepsia etc. Ayurveda practices strictly recommend the use therapeutics only after proper shodhana (purificatory procedure) thr...

The tree diversity and carbon stock of all woody plants were investigated in two-hectare square plots (100 m x 100 m) established Suryanpet (SP) Velleripet (VP) which is tropical dry evergreen forest (TDEF) sites on the Coromandel Coast peninsular India. All trees ? 10 cm girth at breast height measured 1.3 from rooting point enumerated. A total 35 species (? gbh) belonging to 34 genera 23 fami...

Strychnos henningsii Gilg is recommended among other remedies for the treatment of diabetes in traditional medicine of Southern Africa. The antidiabetic effect of oral administration of aqueous bark extract of the plant at 125, 250 and 500 mg/Kg body weight was investigated in diabetic rats induced with streptozotocin-nicotinamide for 15 days. The extract decreased the blood glucose level, feed...

Nuclear effects in neutrino-nucleus reactions simulated by means of the NUX+FLUKA Monte Carlo generator are compared with the theoretical predictions of the Marteau model. Pion absorption in NUX+FLUKA and non-pionic ∆ decays in the Marteau model differ by about 30%. The fraction of pions produced due to the re-interactions after primary quasi-elastic vertex is in the NUX+FLUKA scheme much highe...

Plants in Kenya are becoming increasingly important as sources of traditional medicines. The World Health Organization (WHO) has estimated that malaria kills about 2.7 million people every year, 90% of who are from Africa. Malaria continues to be a national concern in Kenya as it plays a major role in the high mortality rates being experienced currently. The use and mis-use of chloroquine to pr...

Purpose: To investigate the effect of vomit seed homeopathic drugs (14CH and 30CH) on paracetamolinduced toxicity in rats.
 Methods: Thirty-two male Wistar rats were divided into 4 groups 8 animals each (n = 8) treated for 12 days. During treatment period, group (G) one (G1) which constitutes control received filtered water, whereas two (G2), three (G3), four (G4) gavaged with a toxic dose...

Brucine is the active component in traditional Chinese medicine "Ma-Qian-Zi" (Strychnos nux-vomica Linn), with capabilities of analgesic, anti-inflammatory, anti-tumor and so on. It is crucial how to break through the impact of cuticle skin which reduces the penetration of drugs to improve drug transmission rate. The aim of this study is to improve the local drug concentration by using ultrasou...